Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 6/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.35 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.35 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.35 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25008019 | 0.87 | PNMT (0.37) | — | |
| SCHEMBL13120828 | 0.69 | PPARA (0.47) | KCNH2ALDH1A1PLAAT3PLAAT5PLAAT2 | |
| SCHEMBL20708183 | 0.69 | AOC3 (0.42) | KCNH2ALDH1A1PLAAT3PLAAT5PLAAT2 | |
| SCHEMBL4659398 | 0.66 | PLAAT3 (0.45) | ALDH1A1PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL4660647 | 0.66 | PLAAT3 (0.45) | ALDH1A1PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL19314647 | 0.65 | BDKRB2 (0.33) | — | |
| SCHEMBL25006433 | 0.64 | NQO2 (0.38) | ALDH1A1MMP2CTSKSLC6A2SLC6A4 | |
| SCHEMBL53919 | 0.64 | KCNH2 (0.61) | KCNH2ALDH1A1HPGDCA1CA2 | |
| SCHEMBL2056149 | 0.62 | KCNH2 (0.70) | KCNH2ALDH1A1CA2PPARASLC6A2 | |
| SCHEMBL7946947 | 0.62 | TAAR1 (0.50) | ALDH1A1PLAAT3PLAAT5PLAAT2PLAAT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4129402-A1 | HYDROXYPYRROLIDINE DERIVATIVE AND MEDICINAL APPLICATION THEREOF | Mitsubishi Tanabe Pharma Corporation (JP) | 2023-02-08 | — | — | EP | disclosed |