Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 6/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 6/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.40 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19319111 | 1.00 | ALDH1A1 (0.48) | ALDH1A1KDM4EALOX12RAB9AGAA | |
| SCHEMBL19319108 | 1.00 | ALDH1A1 (0.48) | ALDH1A1KDM4EALOX12RAB9AGAA | |
| SCHEMBL25375819 | 0.81 | GAA (0.50) | GAAMAPKAPK2CNR2MEN1KMT2A | |
| SCHEMBL19658634 | 0.81 | L3MBTL1 (0.50) | ALDH1A1GAAMAPKAPK2CNR2MEN1 | |
| SCHEMBL4855769 | 0.80 | POLB (0.41) | ALDH1A1KDM4EGAACNR2MEN1 | |
| SCHEMBL30482179 | 0.80 | CTSK (0.47) | ALDH1A1MEN1KMT2AROCK2ROCK1 | |
| SCHEMBL19652063 | 0.79 | MEN1 (0.50) | ALDH1A1RAB9AGAAMAPKAPK2CNR2 | |
| SCHEMBL19318485 | 0.78 | L3MBTL1 (0.43) | ALDH1A1KDM4EALOX12RAB9ACNR2 | |
| SCHEMBL19318591 | 0.78 | L3MBTL1 (0.43) | ALDH1A1KDM4EALOX12RAB9ACNR2 | |
| SCHEMBL19318590 | 0.78 | L3MBTL1 (0.43) | ALDH1A1KDM4EALOX12RAB9ACNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170253614-A1 | HEPATITIS C VIRUS INHIBITORS AND USES THEREOF IN PREPARATION OF DRUGS | CHANGZHOU YINSHENG PHARMACEUTICAL CO., LTD. (CN) | 2017-09-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170253614-A1 | HEPATITIS C VIRUS INHIBITORS AND USES THEREOF IN PREPARATION OF DRUGS | HAVCR2, HCCS, LIPC | ALDH1A1 1148/4885KDM4E 3963/4885ALOX12 3755/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.