SCHEMBL19320199

SCHEMBL19320199

Clc1nc(-c2ccc3ccccc3c2)nc2c1oc1ccccc12

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.49
MAPT P10636 9/20 0.46
ALDH1A1 P00352 6/20 0.46
LMNA P02545 5/20 0.46
KMT2A Q03164 5/20 0.46
MEN1 O00255 4/20 0.46
POLB P06746 3/20 0.46
HPGD P15428 2/20 0.46
NPSR1 Q6W5P4 2/20 0.46
GAA P10253 1/20 0.46
CYP1A2 P05177 3/20 0.45
CYP2C19 P33261 3/20 0.45
CYP2C9 P11712 2/20 0.45
NPC1 O15118 1/20 0.45
RAB9A P51151 1/20 0.45
TSHR P16473 3/20 0.42
KDM4E B2RXH2 3/20 0.42
HSD17B10 Q99714 2/20 0.40
USP2 O75604 1/20 0.40
HTT P42858 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20068413 0.91 SMN1; SMN2 (0.48) SMN1; SMN2MAPTALDH1A1LMNAKMT2A
SCHEMBL18688220 0.88 SMN1; SMN2 (0.54) SMN1; SMN2MAPTALDH1A1LMNAKMT2A
SCHEMBL19320200 0.85 MAPT (0.54) SMN1; SMN2MAPTALDH1A1LMNAKMT2A
SCHEMBL30117936 0.84 MAPT (0.56) SMN1; SMN2MAPTALDH1A1LMNAKMT2A
SCHEMBL17022617 0.84 MAPT (0.56) SMN1; SMN2MAPTALDH1A1LMNAKMT2A
SCHEMBL16902206 0.84 MAPT (0.48) MAPTALDH1A1LMNAKMT2AMEN1
SCHEMBL20035360 0.84 TSHR (0.47) SMN1; SMN2MAPTALDH1A1LMNAKMT2A
SCHEMBL6857798 0.82 SMN1; SMN2 (0.50) SMN1; SMN2MAPTALDH1A1LMNAKMT2A
SCHEMBL17305854 0.81 CYP1A2 (0.45) SMN1; SMN2MAPTALDH1A1LMNAKMT2A
SCHEMBL20659756 0.81 PIM1 (0.49) SMN1; SMN2MAPTALDH1A1LMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10381574-B2 Compound for organic electronic element, organic electrical element using compound, and electronic device comprising same DUK SAN NEOLUX CO., LTD. (KR) 2019-08-13 US disclosed
US-20190103561-A1 Compound For Organic Electronic Element, Organic Electrical Element Using Compound, And Electronic Device Comprising Same DUK SAN NEOLUX CO., LTD (KR) 2019-04-04 US disclosed
US-20170256719-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRICAL ELEMENT USING COMPOUND, AND ELECTRONIC DEVICE COMPRISING SAME DUK SAN NEOLUX CO., LTD (KR) 2017-09-07 US disclosed
US-20170256719-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRICAL ELEMENT USING COMPOUND, AND ELECTRONIC DEVICE COMPRISING SAME DUK SAN NEOLUX CO., LTD (KR) 2017-09-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170256719-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRICAL ELEMENT USING COMPOUND, AND ELECTRONIC DEVICE COMPRISING SAME ORAI2, VDAC2, PIEZO1 SMN1; SMN2 741/4885MAPT 954/4885ALDH1A1 1187/4885
US-20190103561-A1 Compound For Organic Electronic Element, Organic Electrical Element Using Compound, And Electronic Device Comprising Same ORAI2, VDAC2, PIEZO1 SMN1; SMN2 741/4885MAPT 954/4885ALDH1A1 1187/4885
US-10381574-B2 Compound for organic electronic element, organic electrical element using compound, and electronic device comprising same ORAI2, VDAC2, PIEZO1 SMN1; SMN2 741/4885MAPT 954/4885ALDH1A1 1187/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.