Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.49 |
| ▸ | MAPT | P10636 | 8/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19320200 | 0.89 | MAPT (0.54) | SMN1; SMN2ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL17022617 | 0.88 | MAPT (0.56) | SMN1; SMN2ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL30117936 | 0.88 | MAPT (0.56) | SMN1; SMN2ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL18688220 | 0.83 | SMN1; SMN2 (0.54) | SMN1; SMN2ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL2217397 | 0.83 | SMN1; SMN2 (0.47) | SMN1; SMN2ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL2216325 | 0.82 | ALDH1A1 (0.47) | SMN1; SMN2ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL19320199 | 0.82 | SMN1; SMN2 (0.49) | SMN1; SMN2ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL20068413 | 0.81 | SMN1; SMN2 (0.48) | SMN1; SMN2ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL15304530 | 0.81 | KMT2A (0.62) | SMN1; SMN2ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL29850525 | 0.81 | KMT2A (0.62) | SMN1; SMN2ALDH1A1MAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8389560-B2 | HCV protease inhibitors | TAIGEN BIOTECHNOLOGY CO., LTD. (TW) | 2013-03-05 | — | — | US | disclosed |
| US-20110065737-A1 | HCV PROTEASE INHIBITORS | TAIGEN BIOTECHNOLOGY CO., LTD. (TW) | 2011-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110065737-A1 | HCV PROTEASE INHIBITORS | RNASE1, HAVCR2, CTRL | SMN1; SMN2 3941/4885ALDH1A1 814/4885MAPT 3434/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.