SCHEMBL19320484

SCHEMBL19320484

C/N=C/c1cc(C(C)C)ccc1O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 3/20 0.49
HTT P42858 5/20 0.48
ALDH1A1 P00352 5/20 0.48
ALOX12 P18054 2/20 0.48
GAA P10253 2/20 0.48
HIF1A Q16665 2/20 0.48
RNASEH1 O60930 1/20 0.46
PTGS1 P23219 2/20 0.46
TRPA1 O75762 1/20 0.46
CACNA1C Q13936 1/20 0.46
KDM4E B2RXH2 5/20 0.39
MAPT P10636 6/20 0.39
SMN1; SMN2 Q16637 3/20 0.39
LMNA P02545 2/20 0.39
HSP90AA1 P07900 1/20 0.38
HSP90AB1 P08238 1/20 0.38
HPGD P15428 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
MDM4 O15151 1/20 0.38
CA1 P00915 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18479694 0.85 MAPT (0.54) TYRHTTALDH1A1ALOX12GAA
SCHEMBL19769038 0.81 SRC (0.49) TYRHTTALDH1A1ALOX12GAA
SCHEMBL19734035 0.79 LMNA (0.48) TYRHTTALDH1A1ALOX12GAA
SCHEMBL18489495 0.78 SIRT2 (0.50) TYRALDH1A1HIF1AKDM4EMAPT
SCHEMBL18489494 0.78 SIRT2 (0.50) TYRALDH1A1HIF1AKDM4EMAPT
SCHEMBL17191769 0.77 GABRA1 (0.42) TYRHTTALDH1A1ALOX12GAA
SCHEMBL19779528 0.77 HTT (0.52) TYRHTTALDH1A1ALOX12GAA
SCHEMBL1527156 0.77 TYR (0.72) TYRHTTALDH1A1ALOX12GAA
SCHEMBL18372477 0.76 AMY1A (0.53) HTTALDH1A1GAAKDM4EMAPT
SCHEMBL16657554 0.76 TYR (0.44) TYRHTTALDH1A1ALOX12GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170255100-A1 DRY FILM STRUCTURE FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. 2017-09-07 US disclosed