SCHEMBL19320587

SCHEMBL19320587

CC(O)(CCC(=O)Nc1cc(NC(=O)CCC(C)(O)C(F)(F)F)cc(S(=O)(=O)O)c1)C(F)(F)F

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACP1 P24666 5/20 0.40
CA1 P00915 3/20 0.40
CA2 P00918 3/20 0.40
LMNA P02545 1/20 0.38
ABCC9 O60706 3/20 0.35
ABCC8 Q09428 3/20 0.35
KCNJ11 Q14654 3/20 0.35
KCNJ8 Q15842 3/20 0.35
PDK1 Q15118 1/20 0.35
PDK2 Q15119 1/20 0.35
PDK3 Q15120 1/20 0.35
PDK4 Q16654 1/20 0.35
RORC P51449 2/20 0.35
MEN1 O00255 1/20 0.35
HTT P42858 1/20 0.35
KMT2A Q03164 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
CA12 O43570 1/20 0.35
CA9 Q16790 1/20 0.35
ALDH1A1 P00352 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17879753 0.95 ACP1 (0.37) ACP1CA1CA2LMNAABCC9
SCHEMBL17883725 0.86 ACP1 (0.42) ACP1CA1CA2LMNARORC
SCHEMBL2280495 0.72 CA1 (0.54) ACP1CA1CA2LMNAMEN1
SCHEMBL1948604 0.71 LMNA (0.47) LMNAMEN1KMT2AALDH1A1TP53
SCHEMBL20110635 0.69 LCK (0.39) PDK1PDK2PDK3PDK4
SCHEMBL17879739 0.68 ACP1 (0.36) ACP1CA1CA2LMNAABCC9
SCHEMBL13714757 0.68 FAAH (0.47) CA1CA2LMNAMEN1KMT2A
SCHEMBL17879726 0.66 MRGPRX4 (0.30)
SCHEMBL17879733 0.65 LCK (0.36) PDK1PDK2PDK3PDK4
SCHEMBL15358877 0.64 CA1 (0.47) CA1CA2RORCMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9869933-B2 Pattern trimming methods ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2018-01-16 US disclosed
US-9760011-B1 Pattern trimming compositions and methods ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2017-09-12 US disclosed
US-20170255102-A1 PATTERN TRIMMING COMPOSITIONS AND METHODS U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2017-09-07 US disclosed
US-20170255103-A1 PATTERN TRIMMING METHODS U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2017-09-07 US disclosed