SCHEMBL1948604

SCHEMBL1948604

CC(C)(C)CCC(=O)Nc1cc(NC(=O)CCC(C)(C)C)cc(NC(=O)CCC(C)(C)C)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.47
HDAC3 O15379 1/20 0.44
HDAC4 P56524 1/20 0.44
HDAC1 Q13547 1/20 0.44
HDAC7 Q8WUI4 1/20 0.44
HDAC2 Q92769 1/20 0.44
HDAC10 Q969S8 1/20 0.44
HDAC11 Q96DB2 1/20 0.44
HDAC8 Q9BY41 1/20 0.44
HDAC6 Q9UBN7 1/20 0.44
HDAC9 Q9UKV0 1/20 0.44
HDAC5 Q9UQL6 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.43
KMT2A Q03164 3/20 0.42
MEN1 O00255 2/20 0.42
HPGD P15428 2/20 0.42
F2R P25116 2/20 0.41
TP53 P04637 1/20 0.41
GAA P10253 2/20 0.41
MAPT P10636 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22667768 0.88 TP53 (0.55) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL9157833 0.82 MAPT (0.60) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL24590187 0.81 HDAC3 (0.58) HDAC3HDAC1HDAC2HDAC6KMT2A
SCHEMBL13233261 0.81 CYP1A1 (0.61) HDAC4L3MBTL1KMT2AMEN1HPGD
SCHEMBL9123188 0.81 POLB (0.64) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL20206570 0.81 NPSR1 (0.44) L3MBTL1KMT2AMEN1ALDH1A1RAB9A
SCHEMBL13233335 0.80 BCHE (0.62) LMNAHDAC3HDAC4HDAC1HDAC7
SCHEMBL12926858 0.80 NPC1 (0.56) HDAC3HDAC11HDAC8HDAC6KMT2A
SCHEMBL19125752 0.80 BCAT2 (0.41) LMNAHDAC3HDAC4HDAC1HDAC7
SCHEMBL13233258 0.79 NLRP3 (0.58) HDAC4KMT2AMEN1HPGDMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1592738-B1 RESIN COMPOSITIONS CIBA HOLDING INC (CH) 2020-07-29 EP disclosed
US-9029446-B2 Clarified polypropylene articles with improved optical properties and/or increased temperature of crystallization BASF SE (DE) 2015-05-12 US disclosed
EP-2510047-B1 CLARIFIED POLYPROPYLENE ARTICLES WITH IMPROVED OPTICAL PROPERTIES AND/OR INCREASED TEMPERATURE OF CRYSTALLIZATION BASF SE (DE) 2014-11-05 EP disclosed
US-8415416-B2 Electret materials BASF SE (DE) 2013-04-09 US disclosed
US-20130012091-A1 Electret Materials BASF SE (DE) 2013-01-10 US disclosed
US-20120184170-A1 Electret Materials CHIN HUI (US) 2012-07-19 US disclosed
US-20110230109-A1 Electret Materials CHIN HUI 2011-09-22 US disclosed
US-20110136950-A1 Clarified Polypropylene Articles with Improved Optical Properties and/or increased temperature of Crystallization BASF SE (DE) 2011-06-09 US disclosed
US-7790793-B2 Amide nucleating agent compositions CIBA SPECIALTY CHEM. CORP. (US) 2010-09-07 US disclosed
US-20080249269-A1 Electret materials CIBA CORP. 2008-10-09 US disclosed
US-20070149663-A1 Resin compositions CIBA SPECIALTY CHEMICALS CORP. 2007-06-28 US disclosed
EP-1592738-A2 RESIN COMPOSITIONS Ciba SC Holding AG (CH) 2005-11-09 EP disclosed
WO-2004072168-A2 RESIN COMPOSITIONS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2004-08-26 WO disclosed