Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.42 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.42 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19322238 | 0.89 | PDE3B (0.45) | L3MBTL1LMNAGRIN2DGRIN3BGRIN1 | |
| SCHEMBL19322244 | 0.86 | PDE3B (0.39) | L3MBTL1LMNAMTNR1AMTNR1BPDE3B | |
| SCHEMBL19322243 | 0.86 | NCOA1 (0.41) | L3MBTL1LMNAMTNR1AMTNR1BPDE3B | |
| SCHEMBL19322240 | 0.85 | MTNR1A (0.42) | L3MBTL1LMNAMTNR1AMTNR1BPDE3B | |
| SCHEMBL19322241 | 0.85 | PDE3B (0.39) | L3MBTL1LMNAMTNR1AMTNR1BPDE3B | |
| SCHEMBL19317482 | 0.83 | AR (0.36) | L3MBTL1LMNAMEN1KMT2AMAPT | |
| SCHEMBL19322245 | 0.82 | KDM4E (0.40) | PDE3BPDE3AMEN1KMT2AALDH1A1 | |
| SCHEMBL17469284 | 0.81 | PDE3B (0.39) | L3MBTL1LMNAPDE3BPDE3AMEN1 | |
| SCHEMBL19317487 | 0.76 | MEN1 (0.36) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL19322108 | 0.76 | ALDH1A1 (0.49) | L3MBTL1MTNR1AMTNR1BMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170253580-A1 | ORGANIC REACTIONS | THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2017-09-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170253580-A1 | ORGANIC REACTIONS | MYC, CYP2E1, CYP3A4 | L3MBTL1 2148/4885LMNA 3689/4885MTNR1A 3861/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.