Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | BRD4 | O60885 | 1/20 | 0.56 |
| ▸ | MET | P08581 | 1/20 | 0.56 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.56 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.56 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 4/20 | 0.55 |
| ▸ | CA9 | Q16790 | 4/20 | 0.55 |
| ▸ | CA2 | P00918 | 2/20 | 0.55 |
| ▸ | CA4 | P22748 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | CA12 | O43570 | 2/20 | 0.52 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14495068 | 0.90 | MET (0.68) | PTGESPOLBBRD4METCA1 | |
| SCHEMBL17281694 | 0.89 | PTGES (0.64) | PTGESPOLBHSD17B10BRD4LPAR1 | |
| SCHEMBL17281691 | 0.87 | PTGES (0.61) | PTGESPOLBHSD17B10BRD4LPAR1 | |
| SCHEMBL675768 | 0.86 | MEN1 (0.57) | PTGESPOLBBRD4METCA1 | |
| SCHEMBL12895855 | 0.85 | MET (0.72) | POLBHSD17B10METCA1CA9 | |
| SCHEMBL9564302 | 0.85 | POLB (0.68) | PTGESPOLBHSD17B10BRD4LPAR1 | |
| SCHEMBL14016924 | 0.84 | CA9 (0.64) | POLBMETCA1CA9CA2 | |
| SCHEMBL20081072 | 0.84 | BRD4 (0.60) | PTGESPOLBBRD4LPAR1LPAR5 | |
| SCHEMBL9803534 | 0.83 | LPAR1 (0.77) | PTGESPOLBHSD17B10BRD4LPAR1 | |
| SCHEMBL17272758 | 0.83 | BRD4 (0.73) | PTGESPOLBBRD4LPAR1LPAR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10450408-B2 | Method for making polyarylaliphaticetherketone polymers and copolymers thereof | KETONEX LIMITED (GB) | 2019-10-22 | — | — | US | disclosed |
| US-20170253696-A1 | METHOD FOR MAKING POLYARYLALIPHATICETHERKETONE POLYMERS AND COPOLYMERS THEREOF | OXFORD PERFORMANCE MATERIALS, INC | 2017-09-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10450408-B2 | Method for making polyarylaliphaticetherketone polymers and copolymers thereof | DAO, DCXR, LOX | PTGES 2171/4885POLB 1166/4885HSD17B10 132/4885 |
| US-20170253696-A1 | METHOD FOR MAKING POLYARYLALIPHATICETHERKETONE POLYMERS AND COPOLYMERS THEREOF | COASY, FRK, PBK | PTGES 2203/4885POLB 813/4885HSD17B10 65/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.