SCHEMBL675768

SCHEMBL675768

CNc1ccc(Oc2ccc(N3C(=O)c4ccc(C(C)=O)cc4C3=O)cc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 5/20 0.57
▸ KMT2A Q03164 5/20 0.57
▸ ALDH1A1 P00352 3/20 0.54
▸ PKM P14618 1/20 0.54
▸ NPSR1 Q6W5P4 1/20 0.54
▸ POLB P06746 2/20 0.53
▸ HPGD P15428 1/20 0.53
▸ MET P08581 1/20 0.53
▸ GFER P55789 1/20 0.51
▸ CA1 P00915 3/20 0.49
▸ CA9 Q16790 3/20 0.49
▸ CA2 P00918 2/20 0.49
▸ CA4 P22748 2/20 0.49
▸ PTGES O14684 1/20 0.47
▸ BRD4 O60885 1/20 0.47
▸ GAA P10253 1/20 0.47
▸ MAPT P10636 1/20 0.47
▸ RAB9A P51151 1/20 0.46
▸ CA12 O43570 1/20 0.46
▸ ESR1 P03372 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13533871 0.92 POLB (0.60) MEN1KMT2AALDH1A1NPSR1POLB
SCHEMBL675762 0.86 POLB (0.54) MEN1KMT2AALDH1A1NPSR1POLB
SCHEMBL14495068 0.86 MET (0.68) MEN1KMT2AALDH1A1POLBMET
SCHEMBL19322288 0.86 PTGES (0.61) MEN1KMT2AALDH1A1POLBMET
SCHEMBL12895855 0.82 MET (0.72) MEN1KMT2AALDH1A1POLBMET
SCHEMBL14016924 0.81 CA9 (0.64) MEN1KMT2AALDH1A1NPSR1POLB
SCHEMBL18874610 0.80 KMT2A (0.56) MEN1KMT2AALDH1A1PKMNPSR1
SCHEMBL14010047 0.80 MEN1 (0.72) MEN1KMT2AALDH1A1PKMNPSR1
SCHEMBL4570499 0.79 MMP13 (0.61) MEN1KMT2AALDH1A1PKMNPSR1
SCHEMBL9564302 0.79 POLB (0.68) MEN1KMT2AALDH1A1NPSR1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11685829-B2 Process for preparing particles of aromatic polymers, particles obtainable by said process and their uses SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2023-06-27 — — US disclosed
US-11685829-B2 Process for preparing particles of aromatic polymers, particles obtainable by said process and their uses SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2023-06-27 — — US disclosed
US-11376815-B2 Multilayer assembly SOLVAY SPECIALTY POLYMERS ITALY S.P.A. (IT) 2022-07-05 — — US disclosed
US-11352499-B2 Sulfone polymer composition SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2022-06-07 — — US disclosed
US-20210214543-A1 FLUOROELASTOMER CURABLE COMPOSITION SOLVAY SPECIALTY POLYMERS ITALY S.P.A. (IT) 2021-07-15 — — US disclosed
US-20210139650-A1 END-CAPPED POLY(ARYL ETHER SULFONE) POLYMERS, POLY(ARYL ETHER SULFONE) BLOCK COPOLYMERS, AND CORRESPONDING SYNTHESIS METHODS SOLVAY SPECIALITY POLYMERS USA, LLC 2021-05-13 — — US disclosed
US-20200362177-A1 FLUOROPOLYMER COMPOSITION SOLVAY SPECIALTY POLYMERS IT (US) 2020-11-19 — — US disclosed
US-20200148880-A1 PROCESS FOR PREPARING PARTICLES OF AROMATIC POLYMERS, PARTICLES OBTAINABLE BY SAID PROCESS AND THEIR USES SOLVAY SPECIALITY POLYMERS USA, LLC 2020-05-14 — — US disclosed
US-20200032060-A1 BLENDS OF AROMATIC POLYMERS AND ADDUCTS OBTAINED THEREFROM SOLVAY SPECIALTY POLYMERS USA (US) 2020-01-30 — — US disclosed
EP-2181159-B1 BLENDS OF AROMATIC POLYIMIDES AND AROMATIC SULFONE POLYMERS SOLVAY SPECIALTY POLYMERS USA (US) 2019-11-13 — — EP disclosed
US-20090069507-A1 Aromatic Polyimide Composition SOLVAY ADVANCED POLYMERS, L.L.C. (US) 2009-03-12 — — US disclosed
US-20090069507-A1 Aromatic Polyimide Composition SOLVAY ADVANCED POLYMERS, L.L.C. (US) 2009-03-12 — — US disclosed
US-20090018244-A1 Water-Based Fluoropolymer Composition SOLVAY SOLEXIS, S.P.A. (IT) 2009-01-15 — — US disclosed
US-20090018244-A1 Water-Based Fluoropolymer Composition SOLVAY SOLEXIS, S.P.A. (IT) 2009-01-15 — — US disclosed
US-20080275162-A1 Ptfe-Based Compositions SOLVAY (SOCIETE ANONYME) (BE) 2008-11-06 — — US disclosed
US-20080275162-A1 Ptfe-Based Compositions SOLVAY (SOCIETE ANONYME) (BE) 2008-11-06 — — US disclosed
US-20080014423-A1 Fluoropolymer Tape, Article Comprising a Fluoropolymer Tape and Process for Manufacturing a Fluoropolymer Tape SOLVAY (SOCIETE ANONYMW (BE) 2008-01-17 — — US disclosed
US-20080014423-A1 Fluoropolymer Tape, Article Comprising a Fluoropolymer Tape and Process for Manufacturing a Fluoropolymer Tape SOLVAY (SOCIETE ANONYMW (BE) 2008-01-17 — — US disclosed
US-20070222108-A1 Aromatic Polyimide Composition and Articles Manufactured Therefrom SOLVAY (SOCIETE ANONYME) (BE) 2007-09-27 — — US disclosed
US-20070222108-A1 Aromatic Polyimide Composition and Articles Manufactured Therefrom SOLVAY (SOCIETE ANONYME) (BE) 2007-09-27 — — US disclosed
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