SCHEMBL1932437

SCHEMBL1932437

CC(NO)c1cn([C@H]2O[C@@H](CO)C(O)C2O)c(=S)[nH]c1=O

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PYGM P11217 3/20 0.50
SLC28A1 O00337 1/20 0.45
SLC28A2 O43868 1/20 0.45
SLC29A1 Q99808 1/20 0.45
SLC28A3 Q9HAS3 1/20 0.45
TK2 O00142 2/20 0.44
P2RY2 P41231 1/20 0.42
CDK1 P06493 1/20 0.41
HPGD P15428 1/20 0.41
CDA P32320 3/20 0.40
MAPT P10636 1/20 0.40
SLC5A2 P31639 1/20 0.40
PAX8 Q06710 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21458099 0.87 PYGM (0.52) PYGMSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL27760732 0.86 PYGM (0.51) PYGMSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL21683245 0.83 PYGM (0.48) PYGMSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL3841360 0.83 PYGM (0.48) PYGMSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL1067013 0.82 PYGM (0.52) PYGMSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL27965304 0.82 PYGM (0.49) PYGMSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL5145484 0.82 PYGM (0.49) PYGMSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL27618439 0.81 PYGM (0.46) PYGMSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL28344680 0.80 PYGM (0.50) PYGMSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL15810706 0.80 PYGM (0.57) PYGMSLC28A1SLC28A2SLC29A1SLC28A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011064354-A2 MICRO-RNA AND TISSUE REPAIR RWTH AACHEN (DE) 2011-06-03 WO disclosed