SCHEMBL21683245

SCHEMBL21683245

CNC(C(=O)O)c1cn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=S)[nH]c1=O

nearest known ligand 0.48

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PYGM P11217 3/20 0.48
SLC28A1 O00337 1/20 0.43
SLC28A2 O43868 1/20 0.43
SLC29A1 Q99808 1/20 0.43
SLC28A3 Q9HAS3 1/20 0.43
TK2 O00142 2/20 0.43
SLC5A2 P31639 1/20 0.41
P2RY2 P41231 1/20 0.41
CDK1 P06493 1/20 0.40
HPGD P15428 1/20 0.39
MAPT P10636 1/20 0.39
CDA P32320 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3841360 1.00 PYGM (0.48) PYGMSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL27708288 0.88 PYGM (0.60) PYGMSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL27618439 0.87 PYGM (0.46) PYGMSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL27810485 0.86 ADORA2A (0.39) PYGMMAPT
SCHEMBL27760732 0.86 PYGM (0.51) PYGMSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL1067013 0.85 PYGM (0.52) PYGMSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL1932437 0.83 PYGM (0.50) PYGMSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL21458099 0.83 PYGM (0.52) PYGMSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL441977 0.81 PYGM (0.48) PYGMSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL20534354 0.81 PYGM (0.48) PYGMSLC28A1SLC28A2SLC29A1SLC28A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101341260-A Multi-component nucleases and methods of use thereof JOHNSON & JOHNSON RES PTY LTD (AU) 2009-01-07 CN claimed
US-20240011084-A1 METHODS FOR FULL-LENGTH REVERSE TRANSCRIPTION PCR OF LONG RNAs CONTAINING MODIFIED RIBONUCLEOSIDES USING A THERMOSTABLE REVERSE TRANSCRIPTASE NORTHWESTERN UNIVERSITY 2024-01-11 US disclosed
WO-2020033416-A1 COMBINED TRANSCRIPTION AND TRANSLATION PLATFORM DERIVED FROM PLANT CHLOROPLASTS NORTHWESTERN UNIVERSITY (US) 2020-02-13 WO disclosed
CN-109793893-A VISTA MODULATORS FOR DIAGNOSIS AND TREATMENT OF CANCER 达特茅斯大学理事会 2019-05-24 CN disclosed
CN-105246507-B VISTA Modulators for Diagnosis and Treatment of Cancer 达特茅斯大学理事会 2019-01-25 CN disclosed
CN-105246507-A VISTA modulators for diagnosis and treatment of cancer DARTMOUTH COLLEGE 2016-01-13 CN disclosed
CN-104072611-A Novel cancer-associated antigen VIVENTIA BIOTECHNOLOGIES INC 2014-10-01 CN disclosed
CN-104001158-A Use of Bv8 and/or EG-VEGF to promote hematopoiesis GENENTECH INC 2014-08-27 CN disclosed
CN-102225194-B Use of Bv8 and/or EG-VEGF to promote hematopoiesis GENENTECH INC 2014-07-16 CN disclosed
CN-102725424-B Self-folding amplification of target nucleic acids RD BIOSCIENCES INC 2014-07-09 CN disclosed
CN-101076594-A Arabidopsis coding genes for proteins involved in sugar and lipid metabolism and methods of use BASF PLANT SCIENCE GMBH (DE) 2007-11-21 CN disclosed
CN-1929833-A Oxydecahydronaphthalene modulators of HM74 AVENTIS PHARMA INC (US) 2007-03-14 CN disclosed
CN-1921845-A Furosemide derivatives as modulators of HM74 and their use for the treatment of inflammation AVENTIS PHARMA INC (US) 2007-02-28 CN disclosed
CN-1898263-A Nucleic acids encoding novel prostaglandin receptor proteins and methods of use thereof AVENTIS PHARMA INC (US) 2007-01-17 CN disclosed
CN-1898389-A Modulators of sugar and lipid metabolism in plants VI BASF PLANT SCIENCE GMBH (DE) 2007-01-17 CN disclosed
CN-1809588-A Novel methods for modulating bone-related activity WYETH CORP (US) 2006-07-26 CN disclosed
CN-1802169-A Use of bv8 and/or EG-VEGF to promote hematopoiesis GENENTECH INC (US) 2006-07-12 CN disclosed
CN-1575338-A Bv8 nucleic acids and polypeptides having mitogenic activity GENENTECH INC (US) 2005-02-02 CN disclosed
CN-1547483-A New use of ARTEMIN, a member of the GDNF ligand family �����ɷ� 2004-11-17 CN disclosed
CN-1347460-A Monolayer and electrode for detecting label-bearing target and method of use thereof UNIV NORTH CAROLINA CHAPEL HILL (US) 2002-05-01 CN disclosed