Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 2/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PRKCI | P41743 | 1/20 | 0.39 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | FBP1 | P09467 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13893459 | 0.78 | PTGES (0.54) | PTGESALOX5PTGS1PTGS2FFAR1 | |
| SCHEMBL9752680 | 0.77 | CYP19A1 (0.51) | PTGESALOX5PTGS1PTGS2FFAR1 | |
| SCHEMBL31040534 | 0.77 | FFAR1 (0.59) | PTGESALOX5PTGS1PTGS2FFAR1 | |
| SCHEMBL31040527 | 0.77 | FFAR1 (0.59) | PTGESALOX5PTGS1PTGS2FFAR1 | |
| SCHEMBL9578138 | 0.76 | CTSL (0.57) | FFAR1MEN1KMT2ACYP3A4HPGD | |
| SCHEMBL9578114 | 0.75 | CYP3A4 (0.54) | ALOX5KMT2ASMPD1CYP3A4USP2 | |
| SCHEMBL9578260 | 0.74 | CYP19A1 (0.46) | ALOX5FFAR1MEN1KMT2ACYP3A4 | |
| SCHEMBL10713091 | 0.74 | CYP3A4 (0.58) | ALOX5MEN1KMT2ACYP3A4HPGD | |
| SCHEMBL10713085 | 0.74 | CYP3A4 (0.58) | ALOX5MEN1KMT2ACYP3A4HPGD | |
| SCHEMBL4487600 | 0.73 | ALDH1A1 (0.47) | MEN1KMT2ASMPD1CYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110130447-A1 | Production of hop extracts having oestrogenic and antiproliferative bioactivity | MAES FRANCIS | 2011-06-02 | — | — | US | disclosed |
| EP-1727555-B1 | PRODUCTION OF HOP EXTRACTS HAVING OESTROGENIC AND ANTIPROLIFERATIVE BIOACTIVITY | METAGENICS BELGIUM BVBA (BE) | 2009-04-29 | — | — | EP | disclosed |
| US-20070110835-A1 | Method for the production of enriched hop extracts having combined oestrogenic and antiproliferative bioactivity | METAGENICS BELGIUM BVBA (BE) | 2007-05-17 | — | — | US | disclosed |
| EP-1727555-A1 | PRODUCTION OF HOP EXTRACTS HAVING OESTROGENIC AND ANTIPROLIFERATIVE BIOACTIVITY | Biodynamics (BE) | 2006-12-06 | — | — | EP | disclosed |
| WO-2005058336-A1 | PRODUCTION OF HOP EXTRACTS HAVING OESTROGENIC AND ANTIPROLIFERATIVE BIOACTIVITY | BIODYNAMICS (BE) | 2005-06-30 | — | — | WO | disclosed |
| EP-1543834-A1 | Production of hop extracts having oestrogenic and antiproliferative bioactivity | Biodynamics (BE) | 2005-06-22 | — | — | EP | disclosed |