Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.50 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.50 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.47 |
| ▸ | PTGES | O14684 | 2/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | PRKCI | P41743 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | TRPM7 | Q96QT4 | 1/20 | 0.43 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.43 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10911582 | 0.83 | CYP19A1 (0.51) | CYP19A1FFAR1PLA2G2APLA2G5ALOX5 | |
| SCHEMBL10912757 | 0.83 | CYP19A1 (0.51) | CYP19A1FFAR1PLA2G2APLA2G5ALOX5 | |
| SCHEMBL13893459 | 0.82 | PTGES (0.54) | FFAR1PLA2G2APLA2G5ALOX5PTGES | |
| SCHEMBL1954867 | 0.82 | CYP19A1 (0.59) | CYP19A1ALOX5PTGS2HPGDNPC1 | |
| SCHEMBL11109182 | 0.77 | PTGS2 (0.55) | FFAR1PLA2G2APLA2G5PTGS2HPGD | |
| SCHEMBL31305304 | 0.77 | CYP19A1 (0.54) | CYP19A1ALOX5PTGS2HPGDNPC1 | |
| SCHEMBL1932507 | 0.77 | PTGES (0.55) | FFAR1ALOX5PTGESPTGS1PTGS2 | |
| SCHEMBL11103507 | 0.76 | PTGS2 (0.56) | FFAR1PLA2G2APLA2G5PTGS1PTGS2 | |
| SCHEMBL20357469 | 0.76 | NPC1 (0.65) | CYP19A1FFAR1PLA2G2APLA2G5ALOX5 | |
| SCHEMBL28001032 | 0.75 | CES2 (0.44) | FFAR1PLA2G2APLA2G5HPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991009595-A1 | ANTI-VIRAL COMPOSITIONS | SMITHKLINE BEECHAM CORPORATION (US) | 1991-07-11 | — | — | WO | disclosed |