Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21296782 | 0.76 | PDE4B (0.41) | ALDH1A1MAPTLMNAMEN1KMT2A | |
| SCHEMBL693588 | 0.76 | FAAH (0.41) | ALDH1A1FAAHPOLBELANESMN1; SMN2 | |
| SCHEMBL19329917 | 0.75 | F2 (0.35) | ALDH1A1MAPTLMNAPOLBELANE | |
| SCHEMBL22951279 | 0.74 | FAAH (0.40) | FAAHPOLBELANESMN1; SMN2MAPK1 | |
| SCHEMBL22501848 | 0.74 | ELANE (0.44) | FAAHPOLBELANESMN1; SMN2MAPK1 | |
| SCHEMBL1864917 | 0.74 | FAAH (0.40) | FAAHPOLBELANESMN1; SMN2MAPK1 | |
| SCHEMBL21296822 | 0.74 | ALDH1A1 (0.44) | ALDH1A1MAPTLMNASMN1; SMN2CYP2C19 | |
| SCHEMBL22233152 | 0.73 | FAAH (0.39) | FAAHPOLBELANEMEN1KMT2A | |
| SCHEMBL28739878 | 0.73 | ELANE (0.42) | FAAHPOLBELANESMN1; SMN2MAPK1 | |
| SCHEMBL362915 | 0.72 | FAAH (0.38) | FAAHPOLBELANEMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017153952-A1 | 5-SULFAMOYL-2-HYDROXYBENZAMIDE DERIVATIVES | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2017-09-14 | — | — | WO | disclosed |