Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 2/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.35 |
| ▸ | USP2 | O75604 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.34 |
| ▸ | SCD | O00767 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28739878 | 0.87 | ELANE (0.42) | FAAHELANEBCHEF2PLAU | |
| SCHEMBL344479 | 0.80 | ALDH1A1 (0.39) | FAAHELANEF2PLAUKLKB1 | |
| SCHEMBL693588 | 0.79 | FAAH (0.41) | FAAHELANEBCHEPOLBABCB1 | |
| SCHEMBL1864917 | 0.78 | FAAH (0.40) | FAAHELANEBCHEPOLBGPR119 | |
| SCHEMBL22501848 | 0.78 | ELANE (0.44) | FAAHELANEBCHEPOLBGPR119 | |
| SCHEMBL22951279 | 0.78 | FAAH (0.40) | FAAHELANEBCHEPOLBABCB1 | |
| SCHEMBL362915 | 0.75 | FAAH (0.38) | FAAHELANEBCHEPOLBABCB1 | |
| SCHEMBL16630273 | 0.75 | GABRA1 (0.40) | FAAHELANEBCHEPOLBGPR119 | |
| SCHEMBL30879097 | 0.75 | FAAH (0.41) | FAAHELANEBCHEPOLBABCB1 | |
| SCHEMBL3815163 | 0.75 | F2 (0.39) | ELANEF2PLAUKLKB1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113301901-B | Tetrazolinone substituted steroids and uses thereof | 北京轩义医药科技有限公司 | 2022-09-09 | — | — | CN | disclosed |
| US-20220089636-A1 | TETRAZOLONE SUBSTITUTED STEROIDS AND USE THEREOF | BEIJING XUANYI PHARMASCIENCES CO., LTD. (CN) | 2022-03-24 | — | — | US | disclosed |
| EP-3911331-A1 | TETRAZOLONE SUBSTITUTED STEROIDS AND USE THEREOF | Beijing Xuanyi Pharmasciences Co., Ltd. (CN) | 2021-11-24 | — | — | EP | disclosed |
| CN-113301901-A | Tetrazolinone substituted steroids and uses thereof | 北京轩义医药科技有限公司 | 2021-08-24 | — | — | CN | disclosed |
| WO-2020150210-A1 | TETRAZOLONE SUBSTITUTED STEROIDS AND USE THEREOF | BEIJING XUANYI PHARMASCIENCES CO., LTD. (CN) | 2020-07-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220089636-A1 | TETRAZOLONE SUBSTITUTED STEROIDS AND USE THEREOF | CACNA1I, TAAR5, TAAR1 | FAAH 642/4885ELANE 3516/4885BCHE 4021/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.