Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19329907 | 0.86 | CYP19A1 (0.45) | CYP19A1KDM4EHPGDNPSR1HSD17B10 | |
| SCHEMBL19329647 | 0.85 | CYP19A1 (0.41) | CYP19A1KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL19329745 | 0.83 | CYP19A1 (0.45) | CYP19A1KDM4EL3MBTL1NPC1RAB9A | |
| SCHEMBL31522284 | 0.76 | KDM4E (0.45) | CYP19A1KDM4EHPGDNPSR1L3MBTL1 | |
| SCHEMBL30704294 | 0.71 | PDE10A (0.45) | KDM4EHPGDL3MBTL1NPC1RAB9A | |
| SCHEMBL29134981 | 0.71 | RAB9A (0.43) | CYP19A1KDM4EHPGDL3MBTL1RAB9A | |
| SCHEMBL29134982 | 0.71 | PDE10A (0.45) | KDM4EHPGDL3MBTL1NPC1RAB9A | |
| SCHEMBL29387435 | 0.70 | SMN1; SMN2 (0.43) | KDM4EHPGDNPSR1NPC1RAB9A | |
| SCHEMBL4865308 | 0.70 | SMN1; SMN2 (0.43) | KDM4EHPGDNPSR1NPC1RAB9A | |
| SCHEMBL19330015 | 0.70 | OXER1 (0.47) | KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10940468-B2 | Nickel catalyst, process for preparation and use thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2021-03-09 | — | — | US | disclosed |
| WO-2017154022-A1 | NOVEL NICKEL CATALYST, PROCESS FOR PREPARATION AND USE THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2017-09-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10940468-B2 | Nickel catalyst, process for preparation and use thereof | NISCH, NIT2, C9 | CYP19A1 84/4885KDM4E 2876/4885HPGD 416/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.