Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2010261 | 0.79 | MAPK1 (0.35) | — | |
| SCHEMBL6727805 | 0.65 | KMT2A (0.32) | KMT2ABRD4 | |
| SCHEMBL6738987 | 0.64 | BRD4 (0.38) | KMT2ABRD4 | |
| SCHEMBL2761099 | 0.63 | BRD4 (0.39) | KMT2ABRD4 | |
| SCHEMBL6731347 | 0.60 | MAPT (0.33) | BRD4 | |
| SCHEMBL6730795 | 0.60 | CYP1A2 (0.33) | KMT2ABRD4 | |
| SCHEMBL6730732 | 0.60 | LMNA (0.34) | BRD4 | |
| SCHEMBL4044008 | 0.60 | MAPKAPK2 (0.43) | KMT2ABRD4 | |
| SCHEMBL1820973 | 0.60 | DNTT (0.34) | KMT2ABRD4 | |
| SCHEMBL22969650 | 0.59 | ALDH1A1 (0.38) | KMT2ABRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2504324-A1 | SULTAM DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2012-10-03 | — | — | EP | disclosed |
| WO-2011067266-A1 | CARBOXYLIC ACID ANALOGS AS GLYCOGEN SYNTHASE ACTIVATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2011-06-09 | — | — | WO | disclosed |
| WO-2011064141-A1 | SULTAM DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2011-06-03 | — | — | WO | disclosed |