Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1A | P07327 | 4/20 | 0.44 |
| ▸ | ADH1C | P00326 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | SHBG | P04278 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ADH1B | P00325 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24693895 | 0.90 | DRD2 (0.33) | ADH1AADH1CDRD2DRD3 | |
| SCHEMBL14398636 | 0.85 | KMT2A (0.35) | ADH1AADH1CKMT2ASHBGHSD17B10 | |
| SCHEMBL17914487 | 0.83 | ADH1A (0.47) | ADH1AADH1CKMT2ASHBGADH1B | |
| SCHEMBL19333354 | 0.82 | KMT2A (0.34) | ADH1AADH1CKMT2ASHBGHSD17B10 | |
| SCHEMBL17914491 | 0.81 | ADH1A (0.45) | ADH1AADH1CADH1BDRD2DRD3 | |
| SCHEMBL23319725 | 0.80 | SHBG (0.35) | ADH1AADH1CKMT2ASHBGHSD17B10 | |
| SCHEMBL23319709 | 0.78 | SHBG (0.32) | ADH1AADH1CKMT2ASHBGADH1B | |
| SCHEMBL896726 | 0.76 | SHBG (0.42) | ADH1AADH1CKMT2ASHBGADH1B | |
| SCHEMBL19879075 | 0.76 | ADH1A (0.37) | ADH1AADH1CADH1BCYP1A2 | |
| SCHEMBL19333316 | 0.74 | ADH1A (0.40) | ADH1AADH1CSHBGSLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9758492-B2 | IDO inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-09-12 | — | — | US | disclosed |