Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 3/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.48 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 5/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2737218 | 0.82 | L3MBTL1 (0.56) | PTGS1PTGS2SLC22A12GAAHSD17B10 | |
| SCHEMBL19333346 | 0.81 | CA2 (0.47) | PTGS1PTGS2SLC22A12CA2CA1 | |
| SCHEMBL17917629 | 0.81 | PTGS1 (0.54) | PTGS1PTGS2SLC22A12GAAPTPN1 | |
| SCHEMBL29594713 | 0.79 | ALDH1A1 (0.56) | PTGS1PTGS2SLC22A12MAPTKMT2A | |
| SCHEMBL13129161 | 0.75 | L3MBTL1 (0.64) | PTGS1PTGS2SLC22A12CA2CA1 | |
| SCHEMBL19364119 | 0.75 | GAA (0.64) | GAAHSD17B10MAPTKMT2AMEN1 | |
| SCHEMBL19407723 | 0.73 | CYP2D6 (0.51) | GAAHSD17B10MAPTCA2CA1 | |
| SCHEMBL10416897 | 0.72 | PTGS1 (0.58) | PTGS1PTGS2SLC22A12PTPN1KMT2A | |
| SCHEMBL15116359 | 0.72 | PTPN1 (0.73) | PTGS1PTGS2SLC22A12GAAMAPT | |
| SCHEMBL10933116 | 0.70 | ALDH1A1 (0.43) | PTGS1PTGS2GAAHSD17B10CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9758492-B2 | IDO inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-09-12 | — | — | US | disclosed |