Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 6/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.42 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15503304 | 0.82 | L3MBTL1 (0.59) | PTGS2PTGS1RECQLL3MBTL1POLB | |
| SCHEMBL19333319 | 0.81 | PTGS1 (0.48) | CA2CA1PTGS2PTGS1SLC22A12 | |
| SCHEMBL2737251 | 0.79 | L3MBTL1 (0.44) | RECQLL3MBTL1POLBPSEN1PSEN2 | |
| SCHEMBL13129161 | 0.79 | L3MBTL1 (0.64) | CA2CA1PTGS2PTGS1L3MBTL1 | |
| SCHEMBL17917630 | 0.79 | CA2 (0.50) | CA2CA1PTGS2PTGS1 | |
| SCHEMBL10625554 | 0.78 | CA2 (0.66) | CA2CA1PTGS2PTGS1 | |
| SCHEMBL6658979 | 0.76 | CA2 (0.67) | CA2CA1PTGS2PTGS1SMN1; SMN2 | |
| SCHEMBL24435766 | 0.75 | LMNA (0.35) | CA2CA1SMN1; SMN2PSEN1PSEN2 | |
| SCHEMBL10933116 | 0.73 | ALDH1A1 (0.43) | CA2CA1PTGS2PTGS1PTPN11 | |
| SCHEMBL23876095 | 0.72 | RECQL (0.44) | RECQLPOLBPSEN1PSEN2APH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9758492-B2 | IDO inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-09-12 | — | — | US | disclosed |