Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.30 |
| ▸ | RAB9A | P51151 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6441866 | 1.00 | MAOA (0.38) | MAOAMAOBMAPTMAPK1RAB9A | |
| SCHEMBL18816780 | 1.00 | MAOA (0.38) | MAOAMAOBMAPTMAPK1RAB9A | |
| SCHEMBL5101353 | 1.00 | MAOA (0.38) | MAOAMAOBMAPTMAPK1RAB9A | |
| SCHEMBL2587972 | 0.82 | MAOA (0.46) | MAOAMAOBPOLBMEN1GAA | |
| SCHEMBL13063447 | 0.82 | GPR3 (0.35) | MAOAMAOBPOLBMEN1GAA | |
| SCHEMBL16534568 | 0.77 | ALDH1A1 (0.35) | MAPTRAB9ANPC1POLBMEN1 | |
| SCHEMBL10262549 | 0.73 | HSP90AA1 (0.33) | MAOAMAOBMEN1KMT2A | |
| SCHEMBL18536392 | 0.71 | — | — | |
| SCHEMBL18797963 | 0.71 | MAOA (0.34) | MAOAMAOBMAPTPOLBMEN1 | |
| SCHEMBL5101423 | 0.71 | MAOA (0.34) | MAOAMAOBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9758492-B2 | IDO inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-09-12 | — | — | US | disclosed |