Sugi Predict

Sugi Predict / Compounds / SCHEMBL2587972

SCHEMBL2587972

SCHEMBL2587972

OC1OC(O)c2ccccc21

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAOA P21397 1/20 0.46
▸ MAOB P27338 1/20 0.46
▸ MEN1 O00255 2/20 0.36
▸ KMT2A Q03164 2/20 0.36
▸ GAA P10253 1/20 0.36
▸ ATM Q13315 1/20 0.33
▸ POLB P06746 1/20 0.32
▸ IDO1 P14902 1/20 0.32
▸ GUSB P08236 3/20 0.32
▸ HDAC3 O15379 1/20 0.31
▸ HDAC4 P56524 1/20 0.31
▸ HDAC1 Q13547 1/20 0.31
▸ HDAC7 Q8WUI4 1/20 0.31
▸ HDAC2 Q92769 1/20 0.31
▸ HDAC10 Q969S8 1/20 0.31
▸ HDAC11 Q96DB2 1/20 0.31
▸ HDAC8 Q9BY41 1/20 0.31
▸ HDAC6 Q9UBN7 1/20 0.31
▸ HDAC9 Q9UKV0 1/20 0.31
▸ HDAC5 Q9UQL6 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18816780 0.82 MAOA (0.38) MAOAMAOBMEN1KMT2AGAA
SCHEMBL5101353 0.82 MAOA (0.38) MAOAMAOBMEN1KMT2AGAA
SCHEMBL6441866 0.82 MAOA (0.38) MAOAMAOBMEN1KMT2AGAA
SCHEMBL19333348 0.82 MAOA (0.38) MAOAMAOBMEN1KMT2AGAA
SCHEMBL27611542 0.78 MAOA (0.35) MAOAMAOBATM
SCHEMBL6443068 0.77 MAOA (0.34) MAOAMAOBMEN1KMT2A
SCHEMBL5094185 0.77 MAOA (0.34) MAOAMAOBMEN1KMT2APOLB
SCHEMBL18797963 0.77 MAOA (0.34) MAOAMAOBMEN1KMT2APOLB
SCHEMBL5101423 0.77 MAOA (0.34) MAOAMAOBMEN1KMT2A
SCHEMBL11170220 0.75 MAOA (0.33) MAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023194883-A1 COPOLYMERIZATION OF ORTHO-PHTHALDEHYDE WITH MONOMERS KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY (SA) 2023-10-12 — — WO disclosed
CN-108027564-A Photosensitive polyimide composition 富士胶片电子材料美国有限公司 2018-05-11 — — CN disclosed
EP-2563411-B9 SYNERGYSTIC, NON-EQUILIBRIUM ALDEHYDE BIOCIDES WHITELEY CORP PTY LTD (AU) 2017-07-12 — — EP disclosed
EP-2563411-B1 SYNERGYSTIC, NON-EQUILIBRIUM ALDEHYDE BIOCIDES WHITELEY CORP PTY LTD (AU) 2017-03-01 — — EP disclosed
US-20160266138-A1 FLUIDIC SEPARATION AND DETECTION CAMBRIDGE ENTERPRISE LIMITED (GB) 2016-09-15 — — US disclosed
US-20160266138-A1 FLUIDIC SEPARATION AND DETECTION CAMBRIDGE ENTERPRISE LIMITED (GB) 2016-09-15 — — US disclosed
WO-2016045205-A1 STRENGTHENING AGENT FOR SILK-SCREEN PRINTING PLATE, USE METHOD AND STRENGTHENED PRINTING PLATE 村上精密制版（昆山）有限公司 2016-03-31 — — WO disclosed
US-9175002-B2 Synthesis and use of dual tyrosyl-DNA phosphodiesterase I (Tdp1)—topoisomerase I (Top1) inhibitors PURDUE RESEARCH FOUNDATION (US) 2015-11-03 — — US disclosed
US-9175002-B2 Synthesis and use of dual tyrosyl-DNA phosphodiesterase I (Tdp1)—topoisomerase I (Top1) inhibitors PURDUE RESEARCH FOUNDATION (US) 2015-11-03 — — US disclosed
CN-103079600-B Non-equilibrium Synergistic type aldehydes antimicrobial WHITELEY CORPORATION PTY LTD. (AU) 2015-09-09 — — CN disclosed
US-20150133445-A1 SYNTHESIS AND USE OF DUAL TYROSYL-DNA PHOSPHODIESTERASE I (Tdp1) - TOPOISOMERASE I (Top1) INHIBITORS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2015-05-14 — — US disclosed
US-20150133445-A1 SYNTHESIS AND USE OF DUAL TYROSYL-DNA PHOSPHODIESTERASE I (Tdp1) - TOPOISOMERASE I (Top1) INHIBITORS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2015-05-14 — — US disclosed
CN-104317165-A Reinforcing agent for silk-screen printing plate, application method and printing plate after reinforcing MURAKAMI PREC STENCIL KUNSHAN CO LTD 2015-01-28 — — CN disclosed
US-8933008-B2 Disinfectant solution comprising synergistic, non-equilibrium aldehyde biocides WHITELEY CORPORATION PTY. LTD. (AU) 2015-01-13 — — US disclosed
US-8871893-B2 Signal-responsive plastics THE PENN STATE RESEARCH FOUNDATION (US) 2014-10-28 — — US disclosed
US-20140242623-A1 SIGNAL-RESPONSIVE PLASTICS THE PENN STATE RESEARCH FOUNDATION 2014-08-28 — — US disclosed
US-20130203845-A1 Synergistic, Non-Equilibrium Aldehyde Biocides WHITELEY CORPORATION PTY LTD. (AU) 2013-08-08 — — US disclosed
CN-103079600-A Synergystic, non-equilibrium aldehyde biocides WHITELEY CORP PTY LTD 2013-05-01 — — CN disclosed
EP-2563411-A1 SYNERGYSTIC, NON-EQUILIBRIUM ALDEHYDE BIOCIDES Whiteley Corporation Pty Ltd (AU) 2013-03-06 — — EP disclosed
WO-2011134005-A1 SYNERGYSTIC, NON-EQUILIBRIUM ALDEHYDE BIOCIDES WHITELEY CORPORATION PTY LTD (AU) 2011-11-03 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150133445-A1 SYNTHESIS AND USE OF DUAL TYROSYL-DNA PHOSPHODIESTERASE I (Tdp1) - TOPOISOMERASE I (Top1) INHIBITORS TDP1, TOP1, TDP2 MAOA 720/4885MAOB 711/4885MEN1 3243/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.