Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MLYCD | O95822 | 2/20 | 0.38 |
| ▸ | EBP | Q15125 | 2/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
| ▸ | FDPS | P14324 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19129470 | 0.86 | TAAR1 (0.58) | SIGMAR1TAAR1AOC3KDM4E | |
| SCHEMBL19364108 | 0.85 | TAAR1 (0.46) | SIGMAR1TAAR1AOC3KDM4EEBP | |
| SCHEMBL14065247 | 0.79 | TAAR1 (0.50) | SIGMAR1TAAR1AOC3 | |
| SCHEMBL15701702 | 0.78 | — | — | |
| SCHEMBL17917639 | 0.77 | FDPS (0.58) | SIGMAR1TAAR1AOC3EBPFDPS | |
| SCHEMBL26239740 | 0.77 | AOC3 (0.56) | SIGMAR1TAAR1AOC3KDM4E | |
| SCHEMBL9114952 | 0.77 | ALDH1A1 (0.49) | SIGMAR1TAAR1AOC3KDM4E | |
| SCHEMBL14064920 | 0.75 | AOC3 (0.62) | SIGMAR1TAAR1AOC3KDM4E | |
| SCHEMBL8828293 | 0.75 | MAOA (0.50) | SIGMAR1TAAR1AOC3 | |
| SCHEMBL28948757 | 0.73 | TAAR1 (0.44) | SIGMAR1TAAR1AOC3KDM4EEBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9758492-B2 | IDO inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-09-12 | — | — | US | disclosed |