Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15143531 | 0.84 | MAPT (0.50) | ALDH1A1KMT2AMAPTMEN1HTT | |
| SCHEMBL19334754 | 0.82 | MEN1 (0.41) | ALDH1A1KMT2AMAPTMEN1HTT | |
| SCHEMBL19334755 | 0.82 | ALDH1A1 (0.44) | ALDH1A1KMT2AMAPTMEN1HTT | |
| SCHEMBL19334766 | 0.80 | MAPT (0.42) | ALDH1A1KMT2AMAPTMEN1HTT | |
| SCHEMBL5766444 | 0.73 | KDM4E (0.46) | ALDH1A1KMT2AMAPTMEN1HTT | |
| SCHEMBL30040053 | 0.71 | ELANE (0.61) | ALDH1A1KMT2AMAPTMEN1HTT | |
| SCHEMBL30610014 | 0.71 | ELANE (0.61) | ALDH1A1KMT2AMAPTMEN1HTT | |
| SCHEMBL26768612 | 0.71 | CA12 (0.46) | HTTKDM4ELMNAEGFRHSD17B3 | |
| SCHEMBL26187210 | 0.71 | ELANE (0.61) | ALDH1A1KMT2AMAPTMEN1HTT | |
| SCHEMBL5763637 | 0.70 | ACHE (0.52) | ALDH1A1KMT2AMEN1HTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9758515-B2 | Substituted polycyclic carbamoyl pyridone derivative prodrug | SHIONOGI & CO., LTD. (JP) | 2017-09-12 | — | — | US | disclosed |