Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1933594 | 1.00 | ALDH1A1 (0.64) | ALDH1A1KMT2ALMNAMAPTMAOB | |
| SCHEMBL1932741 | 0.93 | ALDH1A1 (0.55) | ALDH1A1KMT2ALMNAMAPTMAOB | |
| SCHEMBL1932739 | 0.93 | ALDH1A1 (0.55) | ALDH1A1KMT2ALMNAMAPTMAOB | |
| SCHEMBL8956933 | 0.91 | ALDH1A1 (0.54) | ALDH1A1KMT2ALMNAMAPTMAOB | |
| SCHEMBL8956925 | 0.91 | ALDH1A1 (0.54) | ALDH1A1KMT2ALMNAMAPTMAOB | |
| SCHEMBL12699925 | 0.87 | ALDH1A1 (0.69) | ALDH1A1KMT2ALMNAMAPTMEN1 | |
| SCHEMBL984789 | 0.87 | ALDH1A1 (0.69) | ALDH1A1KMT2ALMNAMAPTMEN1 | |
| SCHEMBL1933484 | 0.87 | ALDH1A1 (0.69) | ALDH1A1KMT2ALMNAMAPTMEN1 | |
| SCHEMBL23776044 | 0.83 | ALDH1A1 (0.48) | ALDH1A1KMT2ALMNAMAPTMAOB | |
| SCHEMBL10047332 | 0.83 | ALDH1A1 (0.68) | ALDH1A1KMT2ALMNAMAPTMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8323356-B2 | Sulfonimines as bleaching activators | HENKEL AG & CO. KGAA (DE) | 2012-12-04 | — | — | US | claimed |
| EP-2503984-A1 | SULFONIMINES AS BLEACHING ACTIVATORS | Henkel AG & Co. KGaA (DE) | 2012-10-03 | — | — | EP | claimed |
| US-20120227756-A1 | SULFONIMINES AS BLEACHING ACTIVATORS | HENKEL AG & CO. KGAA (DE) | 2012-09-13 | — | — | US | claimed |
| WO-2011064007-A1 | SULFONIMINES AS BLEACHING ACTIVATORS | HENKEL AG & CO. KGAA (DE) | 2011-06-03 | — | — | WO | claimed |
| EP-2503984-B1 | SULFONIMINES AS BLEACHING ACTIVATORS | HENKEL AG & CO KGAA (DE) | 2017-11-08 | — | — | EP | disclosed |
| US-8815935-B2 | Inhibitors of protein prenyltransferases | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-08-26 | — | — | US | disclosed |
| US-20130102639-A1 | INHIBITORS OF PROTEIN PRENYLTRANSFERASES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-04-25 | — | — | US | disclosed |
| US-8323356-B2 | Sulfonimines as bleaching activators | HENKEL AG & CO. KGAA (DE) | 2012-12-04 | — | — | US | disclosed |
| EP-2503984-A1 | SULFONIMINES AS BLEACHING ACTIVATORS | Henkel AG & Co. KGaA (DE) | 2012-10-03 | — | — | EP | disclosed |
| US-20120227756-A1 | SULFONIMINES AS BLEACHING ACTIVATORS | HENKEL AG & CO. KGAA (DE) | 2012-09-13 | — | — | US | disclosed |
| US-20110178138-A1 | INHIBITORS OF PROTEIN PRENYLTRANSFERASES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2011-07-21 | — | — | US | disclosed |
| WO-2011064007-A1 | SULFONIMINES AS BLEACHING ACTIVATORS | HENKEL AG & CO. KGAA (DE) | 2011-06-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130102639-A1 | INHIBITORS OF PROTEIN PRENYLTRANSFERASES | RABGGTA, FNTA, RABGGTB | ALDH1A1 2160/4885KMT2A 2553/4885LMNA 3093/4885 |
| US-20120227756-A1 | SULFONIMINES AS BLEACHING ACTIVATORS | KRT18, SQOR, GPX4 | ALDH1A1 232/4885KMT2A 430/4885LMNA 2577/4885 |
| US-20110178138-A1 | INHIBITORS OF PROTEIN PRENYLTRANSFERASES | RABGGTA, FNTA, RABGGTB | ALDH1A1 2160/4885KMT2A 2553/4885LMNA 3093/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.