Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 3/20 | 0.51 |
| ▸ | CA2 | P00918 | 3/20 | 0.51 |
| ▸ | CA9 | Q16790 | 3/20 | 0.51 |
| ▸ | CA1 | P00915 | 2/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | F2 | P00734 | 2/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.47 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1933609 | 1.00 | ALDH1A1 (0.57) | ALDH1A1KMT2ALMNASMN1; SMN2CA12 | |
| SCHEMBL1933550 | 0.95 | ALDH1A1 (0.55) | ALDH1A1KMT2ALMNASMN1; SMN2CA12 | |
| SCHEMBL1933547 | 0.95 | ALDH1A1 (0.55) | ALDH1A1KMT2ALMNASMN1; SMN2CA12 | |
| SCHEMBL19547286 | 0.94 | CA12 (0.56) | ALDH1A1KMT2ACA12CA2CA9 | |
| SCHEMBL19547284 | 0.94 | CA12 (0.56) | ALDH1A1KMT2ACA12CA2CA9 | |
| SCHEMBL8854319 | 0.86 | ALDH1A1 (0.62) | ALDH1A1KMT2ALMNACA12CA2 | |
| SCHEMBL19547273 | 0.86 | PTGS2 (0.50) | ALDH1A1CA12CA2CA9CA1 | |
| SCHEMBL19547270 | 0.86 | PTGS2 (0.50) | ALDH1A1CA12CA2CA9CA1 | |
| SCHEMBL19547274 | 0.86 | CA12 (0.50) | ALDH1A1KMT2ACA12CA2CA9 | |
| SCHEMBL19547275 | 0.86 | PTGS2 (0.50) | ALDH1A1CA12CA2CA9CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8323356-B2 | Sulfonimines as bleaching activators | HENKEL AG & CO. KGAA (DE) | 2012-12-04 | — | — | US | claimed |
| EP-2503984-A1 | SULFONIMINES AS BLEACHING ACTIVATORS | Henkel AG & Co. KGaA (DE) | 2012-10-03 | — | — | EP | claimed |
| US-20120227756-A1 | SULFONIMINES AS BLEACHING ACTIVATORS | HENKEL AG & CO. KGAA (DE) | 2012-09-13 | — | — | US | claimed |
| WO-2011064007-A1 | SULFONIMINES AS BLEACHING ACTIVATORS | HENKEL AG & CO. KGAA (DE) | 2011-06-03 | — | — | WO | claimed |
| EP-2503984-B1 | SULFONIMINES AS BLEACHING ACTIVATORS | HENKEL AG & CO KGAA (DE) | 2017-11-08 | — | — | EP | disclosed |
| US-8323356-B2 | Sulfonimines as bleaching activators | HENKEL AG & CO. KGAA (DE) | 2012-12-04 | — | — | US | disclosed |
| EP-2503984-A1 | SULFONIMINES AS BLEACHING ACTIVATORS | Henkel AG & Co. KGaA (DE) | 2012-10-03 | — | — | EP | disclosed |
| US-20120227756-A1 | SULFONIMINES AS BLEACHING ACTIVATORS | HENKEL AG & CO. KGAA (DE) | 2012-09-13 | — | — | US | disclosed |
| WO-2011064007-A1 | SULFONIMINES AS BLEACHING ACTIVATORS | HENKEL AG & CO. KGAA (DE) | 2011-06-03 | — | — | WO | disclosed |
| EP-0946587-A2 | NEW AMIDE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998027108-A2 | NEW AMIDE COMPOUNDS AND THEIR USE AS NITRIC OXIDE SYNTHASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-06-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120227756-A1 | SULFONIMINES AS BLEACHING ACTIVATORS | KRT18, SQOR, GPX4 | ALDH1A1 232/4885KMT2A 430/4885LMNA 2577/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.