Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DTYMK | P23919 | 1/20 | 0.53 |
| ▸ | AKR1C3 | P42330 | 7/20 | 0.52 |
| ▸ | AKR1C2 | P52895 | 7/20 | 0.52 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.52 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.52 |
| ▸ | AKR1C4 | P17516 | 2/20 | 0.52 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | TTR | P02766 | 1/20 | 0.48 |
| ▸ | PPOX | P50336 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30580504 | 0.89 | AKR1C3 (0.63) | DTYMKAKR1C3AKR1C2AKR1B10AKR1B1 | |
| SCHEMBL269614 | 0.89 | AKR1C3 (0.63) | DTYMKAKR1C3AKR1C2AKR1B10AKR1B1 | |
| SCHEMBL18260661 | 0.85 | TDP1 (0.57) | AKR1C3AKR1C2AKR1B10AKR1B1AKR1C4 | |
| SCHEMBL6567226 | 0.80 | KDM4E (0.62) | DTYMKAKR1C3AKR1C2AKR1B10AKR1B1 | |
| SCHEMBL6164746 | 0.80 | ALDH1A1 (0.63) | DTYMKAKR1C3AKR1C2AKR1B10AKR1B1 | |
| SCHEMBL11008714 | 0.80 | KDM4E (0.55) | DTYMKAKR1C3AKR1C2AKR1B10AKR1B1 | |
| SCHEMBL26343222 | 0.79 | DTYMK (0.53) | DTYMKAKR1C3AKR1C2AKR1B10AKR1B1 | |
| SCHEMBL8872227 | 0.79 | MAPT (0.61) | DTYMKMEN1KMT2ATDP1TTR | |
| SCHEMBL8094959 | 0.78 | LMNA (0.48) | DTYMKMEN1KMT2AMAPTKDM4E | |
| SCHEMBL26343209 | 0.78 | DTYMK (0.51) | DTYMKAKR1C3AKR1C2AKR1B10AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170258807-A1 | SUBSTITUTED TRIAZOLOBENZODIAZEPINES | CONCERT PHARMACEUTICALS, INC. (US) | 2017-09-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170258807-A1 | SUBSTITUTED TRIAZOLOBENZODIAZEPINES | BET1, BRD4, BRPF3 | DTYMK 2887/4885AKR1C3 2489/4885AKR1C2 2426/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.