Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | DTYMK | P23919 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31549975 | 0.88 | PKM (0.59) | LMNAPOLBHTTPKML3MBTL1 | |
| SCHEMBL375897 | 0.88 | PKM (0.59) | LMNAPOLBHTTPKML3MBTL1 | |
| Methyl Alcohol SCHEMBL27781670 | 0.87 | PKM (0.58) | LMNAPOLBHTTPKML3MBTL1 | |
| SCHEMBL31151917 | 0.85 | CTSV (0.53) | LMNAPOLBL3MBTL1KDM4EMAPT | |
| SCHEMBL8094915 | 0.84 | POLB (0.52) | LMNAPOLBHTTPKML3MBTL1 | |
| SCHEMBL3663221 | 0.83 | POLB (0.54) | LMNAPOLBHTTPKML3MBTL1 | |
| Methacrylic Acid SCHEMBL28701003 | 0.81 | PKM (0.52) | LMNAPOLBHTTPKML3MBTL1 | |
| SCHEMBL3698713 | 0.81 | PKM (0.52) | LMNAPOLBHTTPKML3MBTL1 | |
| SCHEMBL23734428 | 0.80 | PKM (0.51) | LMNAPOLBHTTPKML3MBTL1 | |
| SCHEMBL2610746 | 0.80 | POLB (0.54) | LMNAPOLBHTTPKML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090062299-A1 | DEUTERIUM-ENRICHED DOXAZOSIN | PROTIA, LLC (US) | 2009-03-05 | — | — | US | disclosed |
| US-20080039473-A1 | PREPARATION AND UTILITY OF SUBSTITUTED QUINAZOLINE COMPOUNDS WITH ALPHA-ADRENERGIC BLOCKING EFFECTS | AUSPEX PHARMACEUTICALS, INC. (US) | 2008-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090062299-A1 | DEUTERIUM-ENRICHED DOXAZOSIN | REN, ADRA1D, QDPR | LMNA 751/4885POLB 2968/4885HTT 1194/4885 |
| US-20080039473-A1 | PREPARATION AND UTILITY OF SUBSTITUTED QUINAZOLINE COMPOUNDS WITH ALPHA-ADRENERGIC BLOCKING EFFECTS | ADRB1, ADRB2, ADRB3 | LMNA 972/4885POLB 2328/4885HTT 4597/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.