Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.45 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.42 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.42 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.40 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.40 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.40 |
| ▸ | TLR2 | O60603 | 4/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.37 |
| ▸ | GSR | P00390 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 2/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.35 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.35 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.34 |
| ▸ | NMT2 | O60551 | 1/20 | 0.34 |
| ▸ | NMT1 | P30419 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10073549 | 0.86 | FOLH1 (0.44) | FOLH1SIRT6SIRT1SLC6A5GNAI3 | |
| SCHEMBL18882588 | 0.86 | FOLH1 (0.44) | FOLH1SIRT6SIRT1SLC6A5GNAI3 | |
| SCHEMBL20196381 | 0.81 | SIRT6 (0.58) | FOLH1SIRT6SIRT1SLC6A5GNAI3 | |
| SCHEMBL14586422 | 0.81 | CASP2 (0.45) | SIRT6SIRT1SLC6A5GNAI3GNAO1 | |
| SCHEMBL2151319 | 0.80 | FOLH1 (0.57) | FOLH1SIRT6SIRT1SLC6A5TLR2 | |
| SCHEMBL16383761 | 0.80 | SIRT6 (0.45) | FOLH1SIRT6SIRT1SLC6A5GNAI3 | |
| SCHEMBL2151316 | 0.80 | FOLH1 (0.57) | FOLH1SIRT6SIRT1SLC6A5TLR2 | |
| SCHEMBL15834023 | 0.80 | FOLH1 (0.45) | FOLH1SIRT6SIRT1SLC6A5GNAI3 | |
| SCHEMBL14342256 | 0.80 | SIRT6 (0.45) | FOLH1SIRT6SIRT1SLC6A5GNAI3 | |
| Hydrochloric Acid SCHEMBL28514579 | 0.79 | FOLH1 (0.56) | FOLH1SIRT6SIRT1SLC6A5TLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170260580-A1 | GENETIC DETECTION PLATFORM | PHARMOZYME, INC. | 2017-09-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170260580-A1 | GENETIC DETECTION PLATFORM | POLN, POLI, POLRMT | FOLH1 1574/4885SIRT6 4307/4885SIRT1 4846/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.