Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 2/20 | 0.46 |
| ▸ | PLK4 | O00444 | 1/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.46 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | LCK | P06239 | 1/20 | 0.46 |
| ▸ | FYN | P06241 | 1/20 | 0.46 |
| ▸ | LYN | P07948 | 1/20 | 0.46 |
| ▸ | RET | P07949 | 1/20 | 0.46 |
| ▸ | ROS1 | P08922 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.46 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.46 |
| ▸ | TYK2 | P29597 | 1/20 | 0.46 |
| ▸ | AXL | P30530 | 1/20 | 0.46 |
| ▸ | FRK | P42685 | 1/20 | 0.46 |
| ▸ | SYK | P43405 | 1/20 | 0.46 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5318462 | 0.81 | MAOB (0.47) | MAPTALDH1A1POLBF10GAA | |
| SCHEMBL1935591 | 0.81 | KMO (0.45) | ALDH1A1KDM4E | |
| SCHEMBL12439744 | 0.81 | KMO (0.45) | ALDH1A1KDM4E | |
| SCHEMBL2337914 | 0.80 | NOS3 (0.50) | ALDH1A1POLBTDP1 | |
| SCHEMBL13847246 | 0.80 | NOS3 (0.50) | ALDH1A1POLBTDP1 | |
| SCHEMBL12446917 | 0.80 | NOS3 (0.50) | ALDH1A1POLBTDP1 | |
| SCHEMBL1935338 | 0.80 | RAF1 (0.40) | KDRPLK4AURKAMAPK13MAP4K4 | |
| SCHEMBL12439738 | 0.80 | RAF1 (0.40) | KDRPLK4AURKAMAPK13MAP4K4 | |
| SCHEMBL2335940 | 0.77 | MAPT (0.40) | RAF1MAPTALDH1A1L3MBTL1POLB | |
| SCHEMBL13028341 | 0.77 | MAPT (0.40) | RAF1MAPTALDH1A1L3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2332936-B1 | PYRIDINE COMPOUND AND USE THEREOF FOR PEST CONTROL | SUMITOMO CHEMICAL CO (JP) | 2013-09-04 | — | — | EP | disclosed |
| US-20110178132-A1 | PYRIDINE COMPOUND AND USE THEREOF FOR PEST CONTROL | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2011-07-21 | — | — | US | disclosed |
| EP-2332936-A1 | PYRIDINE COMPOUND AND USE THEREOF FOR PEST CONTROL | Sumitomo Chemical Company, Limited (JP) | 2011-06-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110178132-A1 | PYRIDINE COMPOUND AND USE THEREOF FOR PEST CONTROL | C5, PRDX1, PRDX4 | KDR 4701/4885PLK4 2056/4885AURKA 3781/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.