Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.48 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14408021 | 0.93 | HPGD (0.49) | USP2SMN1; SMN2ESR2NR1H2HPGD | |
| SCHEMBL1813321 | 0.82 | USP2 (0.56) | USP2SMN1; SMN2ESR2NR1H2HPGD | |
| SCHEMBL3749225 | 0.82 | USP2 (0.56) | USP2SMN1; SMN2ESR2NR1H2HPGD | |
| SCHEMBL27669441 | 0.82 | USP2 (0.56) | USP2SMN1; SMN2ESR2NR1H2HPGD | |
| SCHEMBL31028 | 0.82 | USP2 (0.56) | USP2SMN1; SMN2ESR2NR1H2HPGD | |
| SCHEMBL24818255 | 0.82 | USP2 (0.56) | USP2SMN1; SMN2ESR2NR1H2HPGD | |
| SCHEMBL698803 | 0.81 | USP2 (0.69) | USP2SMN1; SMN2NR1H2HPGDHTT | |
| SCHEMBL18294 | 0.81 | USP2 (0.69) | USP2SMN1; SMN2NR1H2HPGDHTT | |
| SCHEMBL8436771 | 0.81 | USP2 (0.55) | USP2SMN1; SMN2ESR2NR1H2HPGD | |
| SCHEMBL19459157 | 0.81 | USP2 (0.55) | USP2SMN1; SMN2ESR2NR1H2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117247347-A | Preparation method of N-Boc-4-aminopiperidine | 安徽昊帆生物有限公司 | 2023-12-19 | — | — | CN | claimed |
| CN-117247347-A | Preparation method of N-Boc-4-aminopiperidine | 安徽昊帆生物有限公司 | 2023-12-19 | — | — | CN | disclosed |
| CN-117247347-A | Preparation method of N-Boc-4-aminopiperidine | 安徽昊帆生物有限公司 | 2023-12-19 | — | — | CN | disclosed |
| EP-3891136-B1 | 4-HETEROARYLCARBONYL-N-(PHENYL OR HETEROARYL)PIPERIDINE-1-CARBOXAMIDES AS INHIBITORS OF TANKYRASES | MERCK PATENT GMBH (DE) | 2023-07-19 | — | — | EP | disclosed |
| WO-2023133524-A1 | A PROCESS FOR SYNTHESIZING KETANSERIN | TERRAN BIOSCIENCES, INC. (US) | 2023-07-13 | — | — | WO | disclosed |
| US-10428024-B2 | Piperidinyl derivatives | MERCK PATENT GMBH (DE) | 2019-10-01 | — | — | US | disclosed |
| US-20190135753-A1 | PIPERIDINYL DERIVATIVES | MERCK PATENT GMBH (DE) | 2019-05-09 | — | — | US | disclosed |
| WO-2017156177-A1 | 3-PHOSPHOGLYCERATE DEHYDROGENASE INHIBITORS AND USES THEREOF | RAZE THERAPEUTICS, INC. (US) | 2017-09-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10428024-B2 | Piperidinyl derivatives | PDK1, PDK2, PDK3 | USP2 3901/4885SMN1; SMN2 2643/4885ESR2 1142/4885 |
| US-20190135753-A1 | PIPERIDINYL DERIVATIVES | PDK1, PDK2, PDK3 | USP2 3901/4885SMN1; SMN2 2643/4885ESR2 1142/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.