Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.41 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.41 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.41 |
| ▸ | ACP1 | P24666 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11368859 | 0.85 | TSHR (0.70) | TSHRHSD17B10ALDH1A1HPGDTP53 | |
| Sulfuric Acid SCHEMBL4577786 | 0.85 | TSHR (0.70) | TSHRHSD17B10ALDH1A1HPGDTP53 | |
| Diphenylamine SCHEMBL724958 | 0.83 | HSD17B10 (0.52) | TSHRHSD17B10ALDH1A1HPGDCYP3A4 | |
| Sulfuric Acid SCHEMBL8026090 | 0.81 | TSHR (0.64) | TSHRHSD17B10ALDH1A1HPGDTP53 | |
| SCHEMBL22462534 | 0.81 | TSHR (0.70) | TSHRHSD17B10ALDH1A1HPGDTP53 | |
| Trifluoromethanesulfonic Acid SCHEMBL27550260 | 0.79 | LMNA (0.47) | ALDH1A1KEAP1PDK1PDK2PDK3 | |
| Trifluoroacetic Acid SCHEMBL9333894 | 0.79 | TSHR (0.61) | TSHRHSD17B10TP53CYP3A4PDK1 | |
| Trifluoroacetic Acid SCHEMBL584478 | 0.79 | TSHR (0.61) | TSHRHSD17B10TP53CYP3A4PDK1 | |
| Diphenylamine SCHEMBL16291173 | 0.78 | PTGS1 (0.42) | TSHRHSD17B10ALDH1A1HPGDALOX15 | |
| Trifluoromethanesulfonic Acid SCHEMBL25226663 | 0.78 | TSHR (0.46) | TSHRALDH1A1HPGDTP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102702278-B | Method for synthesizing clindamycin 3,4-isopropylidene | UNIV ZHEJIANG TECHNOLOGY | 2015-01-28 | — | — | CN | claimed |
| CN-102702278-A | Method for synthesizing clindamycin 3,4-isopropylidene | UNIV ZHEJIANG TECHNOLOGY | 2012-10-03 | — | — | CN | claimed |
| CN-102702278-B | Method for synthesizing clindamycin 3,4-isopropylidene | UNIV ZHEJIANG TECHNOLOGY | 2015-01-28 | — | — | CN | disclosed |
| US-8921572-B2 | Method for producing 5,5-disubstituted 4,5-dihydroisoxazol-3-thiocarboxamidine salts | BASF SE (DE) | 2014-12-30 | — | — | US | disclosed |
| US-20120264947-A1 | Method for Producing 5,5-Disubstituted 4,5-Dihydroisoxazol-3-Thiocarboxamidine Salts | BASF SE (DE) | 2012-10-18 | — | — | US | disclosed |
| EP-2504322-A1 | METHOD FOR PRODUCING 5,5-DISUBSTITUTED 4,5-DIHYDROISOXAZOL-3-THIOCARBOXAMIDINE SALTS | BASF SE (DE) | 2012-10-03 | — | — | EP | disclosed |
| CN-102702278-A | Method for synthesizing clindamycin 3,4-isopropylidene | UNIV ZHEJIANG TECHNOLOGY | 2012-10-03 | — | — | CN | disclosed |
| WO-2011063842-A1 | METHOD FOR PRODUCING 5,5-DISUBSTITUTED 4,5-DIHYDROISOXAZOL-3-THIOCARBOXAMIDINE SALTS | BASF SE (DE) | 2011-06-03 | — | — | WO | disclosed |
| US-20070048660-A1 | Resist composition, method for forming resist pattern, semiconductor device and method for manufacturing thereof | FUJITSU LIMITED (JP) | 2007-03-01 | — | — | US | disclosed |
| EP-1757983-A1 | Resist composition, method for forming resist pattern, semiconductor device and method for manufacturing thereof | Fujitsu Ltd. (JP) | 2007-02-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120264947-A1 | Method for Producing 5,5-Disubstituted 4,5-Dihydroisoxazol-3-Thiocarboxamidine Salts | DHX15, DHX35, HDHD5 | TSHR 32/4885HSD17B10 2789/4885ALDH1A1 602/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.