Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.50 |
| ▸ | MT-ND4 | P03905 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | GMNN | O75496 | 1/20 | 0.50 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | MTOR | P42345 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1934352 | 1.00 | MAPK1 (0.53) | MAPK1CYP3A4MAPTALDH1A1CYP2C19 | |
| SCHEMBL4124579 | 0.91 | MAPK1 (0.45) | MAPK1CYP3A4MAPTALDH1A1CYP2C19 | |
| SCHEMBL4114087 | 0.89 | MAPT (0.49) | MAPK1CYP3A4MAPTALDH1A1CYP2C19 | |
| SCHEMBL29894504 | 0.74 | CYP1A1 (0.37) | TSHRCYP1A2PTGDR2 | |
| Tubaic Acid SCHEMBL14443999 | 0.71 | MAPK1 (1.00) | MAPK1CYP3A4MAPTALDH1A1CYP2C19 | |
| SCHEMBL12343777 | 0.71 | PTGDR2 (0.38) | HIF1APTGDR2 | |
| SCHEMBL20902712 | 0.69 | MAPT (0.48) | MAPK1CYP3A4MAPTALDH1A1CYP2C19 | |
| SCHEMBL13056618 | 0.69 | CYP3A4 (0.63) | MAPK1CYP3A4MAPTALDH1A1CYP2C19 | |
| SCHEMBL47262 | 0.69 | CYP3A4 (0.63) | MAPK1CYP3A4MAPTALDH1A1CYP2C19 | |
| SCHEMBL10280019 | 0.69 | CYP3A4 (0.63) | MAPK1CYP3A4MAPTALDH1A1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250242030-A1 | COMPOSITIONS COMPRISING A NON-BIOABSORBABLE POLYMER AND METABOLIC INHIBITOR | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2025-07-31 | — | — | US | claimed |
| US-20250135072-A1 | COMPOSITIONS COMPRISING A BIOABSORBABLE POLYMER AND METABOLIC INHIBITOR | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2025-05-01 | — | — | US | claimed |
| CN-116947875-A | Mitochondrion-targeted rotenone-malonic acid-dequalinium chloride compound and preparation method and application thereof | 聊城大学 | 2023-10-27 | — | — | CN | claimed |
| CN-116947936-A | Mitochondrion-targeted rotenone-dequalinium chloride-hyaluronic acid compound and preparation method and application thereof | 聊城大学 | 2023-10-27 | — | — | CN | claimed |
| WO-2023147055-A1 | COMPOSITIONS COMPRISING A NON-BIOABSORBABLE POLYMER AND METABOLIC INHIBITOR | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2023-08-03 | — | — | WO | claimed |
| WO-2023147048-A1 | COMPOSITIONS COMPRISING A BIOABSORBABLE POLYMER AND METABOLIC INHIBITOR | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2023-08-03 | — | — | WO | claimed |
| US-20250242030-A1 | COMPOSITIONS COMPRISING A NON-BIOABSORBABLE POLYMER AND METABOLIC INHIBITOR | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2025-07-31 | — | — | US | disclosed |
| US-20250135072-A1 | COMPOSITIONS COMPRISING A BIOABSORBABLE POLYMER AND METABOLIC INHIBITOR | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2025-05-01 | — | — | US | disclosed |
| US-20240293366-A1 | TOPICAL COMPOSITIONS AND METHODS FOR TREATING INFLAMMATORY SKIN DISEASES | AZORA THERAPEUTICS, INC. | 2024-09-05 | — | — | US | disclosed |
| CN-117398405-A | Anti-depression pharmaceutical composition and application thereof | 重庆市中药研究院 | 2024-01-16 | — | — | CN | disclosed |
| CN-117337138-A | Controlled release delivery compositions for extending shelf life of perishable goods and methods of making and using the same | RYP实验室有限公司 | 2024-01-02 | — | — | CN | disclosed |
| CN-116947875-A | Mitochondrion-targeted rotenone-malonic acid-dequalinium chloride compound and preparation method and application thereof | 聊城大学 | 2023-10-27 | — | — | CN | disclosed |
| CN-116947936-A | Mitochondrion-targeted rotenone-dequalinium chloride-hyaluronic acid compound and preparation method and application thereof | 聊城大学 | 2023-10-27 | — | — | CN | disclosed |
| US-20220023259-A1 | TOPICAL COMPOSITIONS AND METHODS FOR TREATING INFLAMMATORY SKIN DISEASES | AZORA THERAPEUTICS, INC. | 2022-01-27 | — | — | US | disclosed |
| US-11154533-B2 | Topical compositions and methods for treating inflammatory skin diseases | AZORA THERAPEUTICS, INC. (US) | 2021-10-26 | — | — | US | disclosed |
| US-20210186931-A1 | TOPICAL COMPOSITIONS AND METHODS FOR TREATING INFLAMMATORY SKIN DISEASES | AZORA THERAPEUTICS, INC. | 2021-06-24 | — | — | US | disclosed |
| US-8551448-B2 | Rotanone analogs: method of preparation and use | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-10-08 | — | — | US | disclosed |
| WO-2011068416-A1 | METHOD AND DEVICE FOR CLEANING AND DISINFECTING THE OUTSIDE OF A HULL | REDOX AS (NO) | 2011-06-09 | — | — | WO | disclosed |
| US-20090136424-A1 | Rotanone Analogs: Method of Preparation and Use | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2009-05-28 | — | — | US | disclosed |
| WO-2007137135-A2 | ROTENONE ANALOGS: METHOD OF PREPARATION AND USE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-11-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210186931-A1 | TOPICAL COMPOSITIONS AND METHODS FOR TREATING INFLAMMATORY SKIN DISEASES | AHR, ARNT, TLR8 | MAPK1 3008/4885CYP3A4 1246/4885MAPT 1167/4885 |
| US-11154533-B2 | Topical compositions and methods for treating inflammatory skin diseases | AHR, ARNT, TLR8 | MAPK1 3008/4885CYP3A4 1246/4885MAPT 1167/4885 |
| US-20090136424-A1 | Rotanone Analogs: Method of Preparation and Use | NDUFB5, NDUFB10, NDUFB3 | MAPK1 4450/4885CYP3A4 510/4885MAPT 3737/4885 |
| US-20240293366-A1 | TOPICAL COMPOSITIONS AND METHODS FOR TREATING INFLAMMATORY SKIN DISEASES | AHR, ARNT, TLR8 | MAPK1 3008/4885CYP3A4 1246/4885MAPT 1167/4885 |
| US-20220023259-A1 | TOPICAL COMPOSITIONS AND METHODS FOR TREATING INFLAMMATORY SKIN DISEASES | AHR, ARNT, TLR8 | MAPK1 3008/4885CYP3A4 1246/4885MAPT 1167/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.