SCHEMBL1934404

SCHEMBL1934404

CC1=NN(c2ccc([N+](=O)[O-])cc2)C(=O)C1[N+](=O)[O-]

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 11/20 1.00
▸ ALDH1A1 P00352 9/20 1.00
▸ MEN1 O00255 9/20 1.00
▸ KMT2A Q03164 9/20 1.00
▸ KDM4E B2RXH2 4/20 0.56
▸ SMN1; SMN2 Q16637 4/20 0.49
▸ ABCG2 Q9UNQ0 1/20 0.47
▸ PKM P14618 1/20 0.47
▸ ACHE P22303 1/20 0.44
▸ HSD17B10 Q99714 1/20 0.44
▸ AMY1A P0DUB6 1/20 0.43
▸ HTT P42858 3/20 0.43
▸ GAA P10253 2/20 0.43
▸ NPSR1 Q6W5P4 1/20 0.43
▸ L3MBTL1 Q9Y468 1/20 0.43
▸ LOX P28300 1/20 0.42
▸ LOXL3 P58215 1/20 0.42
▸ LOXL4 Q96JB6 1/20 0.42
▸ LOXL2 Q9Y4K0 1/20 0.42
▸ NPC1 O15118 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Barbituric Acid SCHEMBL11227752 0.88 MAPT (0.77) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL5928770 0.80 MAPT (0.67) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL9467010 0.73 MAPT (0.57) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL31579474 0.72 MAPT (1.00) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL31579529 0.72 MAPT (1.00) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL6733051 0.71 MEN1 (0.64) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL9511915 0.71 MAPT (0.55) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL28700332 0.71 MAPT (0.58) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL4664731 0.70 MAPT (0.70) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL23878375 0.69 MAPT (0.51) MAPTALDH1A1MEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 196 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0378373-B1 Photohardenable compositions and their use in producing images MEAD CORP (US) 1997-03-05 — — EP claimed
US-5079126-A Pyrazoline-5-one compound, reduction of reciprocity failure, imaging method, microcapsules coated on support THE MEAD CORPORATION (US) 1992-01-07 — — US claimed
CN-1046331-A The photohardenable composition that contains five member aromatic group with imine moiety MEAD CORP (US) 1990-10-24 — — CN claimed
EP-0378373-A2 Photohardenable compositions and their use in producing images THE MEAD CORPORATION (US) 1990-07-18 — — EP claimed
US-4822891-A ANALYZING HYDROGEN PEROXIDE FUJI PHOTO FILM CO., LTD. (JP) 1989-04-18 — — US claimed
US-4711963-A 4-amino-2-methyl-3-phenyl-1-(2,4,6-trichlorophenyl)-3-pyrazolin-5-one FUJI PHOTO FILM CO., LTD. (JP) 1987-12-08 — — US claimed
US-4353912-A NEUROLEPTIC AGENTS NORTHEASTERN UNIVERSITY (US) 1982-10-12 — — US claimed
US-4028183-A MULTISTAGE, MULTIZONAL; ATP-METHIONINE-ADENOSYL-TRANSFERASE ON ATP BIORESEARCH LIMITED (IT) 1977-06-07 — — US claimed
US-3954726-A Double salts of S-adenosil-L-methionine BIORESEARCH LIMITED (IT) 1976-05-04 — — US claimed
JP-2192466-A — — None — — JP disclosed
US-12577344-B2 One component (1K) composition based on epoxy resin HENKEL AG & CO. KGAA (DE) 2026-03-17 — — US disclosed
US-20260013535-A1 STEVIOL GLYCOSIDE SOLUBILITY ENHANCERS CARGILL, INCORPORATED (US) 2026-01-15 — — US disclosed
US-12458049-B2 Steviol glycoside solubility enhancers CARGILL, INCORPORATED (US) 2025-11-04 — — US disclosed
EP-3916033-B1 ONE COMPONENT (1K) COMPOSITION BASED ON EPOXY RESIN HENKEL AG & CO KGAA (DE) 2025-10-29 — — EP disclosed
US-3963748-A 1-Phenyl-3-azacarbocyclic-ureas STERLING DRUG INC. (US) 1976-06-15 — — US disclosed
US-3960886-A Substituted N-arylanilines STERLING DRUG INC. (US) 1976-06-01 — — US disclosed
US-3959309-A ANALGESICS, PSYCHOTROPIC, ANTIHISTAMINE STERLING DRUG INC. (US) 1976-05-25 — — US disclosed
US-3954726-A Double salts of S-adenosil-L-methionine BIORESEARCH LIMITED (IT) 1976-05-04 — — US disclosed
US-3947395-A Epoxy surface coating compositions HITACHI, LTD. (JA) 1976-03-30 — — US disclosed
US-3940421-A Intermediates for the preparation of thienobenzopyrans and thiopyranobenzopyrans ARTHUR D. LITTLE, INC. (US) 1976-02-24 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12458049-B2 Steviol glycoside solubility enhancers SI, TAS2R7, TAS2R31 MAPT 3044/4885ALDH1A1 2625/4885MEN1 679/4885
US-20260013535-A1 STEVIOL GLYCOSIDE SOLUBILITY ENHANCERS TAS2R7, TAS2R31, TAS2R40 MAPT 1667/4885ALDH1A1 3539/4885MEN1 1131/4885
US-12577344-B2 One component (1K) composition based on epoxy resin CBR1, AGTR1, SMARCC1 MAPT 4584/4885ALDH1A1 225/4885MEN1 1718/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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