Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 13/20 | 0.67 |
| ▸ | MEN1 | O00255 | 12/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 12/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.54 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.43 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5928903 | 0.84 | MAPT (0.48) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL1934404 | 0.80 | MAPT (1.00) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL5928736 | 0.80 | MAPT (0.49) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL5928818 | 0.77 | MEN1 (0.50) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL26821039 | 0.77 | MAPT (0.76) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL26821077 | 0.76 | MAPT (0.59) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL22670032 | 0.76 | POLB (0.49) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL22678453 | 0.74 | MAPT (0.41) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL22670353 | 0.73 | ACSS2 (0.48) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL28700332 | 0.71 | MAPT (0.58) | MAPTMEN1KMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060229324-A1 | Quinazolin-4-one derivatives | INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) | 2006-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060229324-A1 | Quinazolin-4-one derivatives | HPGDS, PTGS1, PTGDR | MAPT 4875/4885MEN1 3991/4885KMT2A 2207/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.