SCHEMBL19345006

SCHEMBL19345006

N#Cc1ccc(-c2ccc(N3c4ccccc4[Si](c4ccccc4)(c4ccccc4)c4ccccc43)cc2)c(C#N)c1

nearest known ligand 0.39

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
STS P08842 1/20 0.39
CYP19A1 P11511 2/20 0.34
CYP11B1 P15538 1/20 0.34
CYP11B2 P19099 1/20 0.34
CNR1 P21554 2/20 0.33
PDCD1 Q15116 1/20 0.33
CD274 Q9NZQ7 1/20 0.33
PGR P06401 1/20 0.32
ESR2 Q92731 1/20 0.31
XDH P47989 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19345075 0.91 CYP19A1 (0.32) STSCYP19A1CYP11B1CYP11B2CNR1
SCHEMBL19345283 0.85 AR (0.37) CYP11B2PGR
SCHEMBL19345015 0.84 ALDH1A1 (0.34) CNR1
SCHEMBL19344948 0.84 TSHR (0.39) PGR
SCHEMBL19345025 0.82 FAAH (0.33) CYP19A1PGR
SCHEMBL19344961 0.81 CA1 (0.32)
SCHEMBL19344988 0.79 KDM4E (0.32)
SCHEMBL20997988 0.79 MGLL (0.40) CYP11B2PDCD1CD274
SCHEMBL19344968 0.79 ALDH1A1 (0.34)
SCHEMBL19345073 0.79 PGR (0.35) CYP19A1CYP11B1CYP11B2CNR1PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170263871-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND ORGANIC OPTOELECTRONIC DEVICE TIANMA MICRO-ELECTRONICS CO., LTD. (CN) 2017-09-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170263871-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND ORGANIC OPTOELECTRONIC DEVICE OR10J3, RPS10, OR51E2 STS 1626/4885CYP19A1 781/4885CYP11B1 1402/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.