Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19346703 | 0.87 | — | — | |
| SCHEMBL19346486 | 0.85 | — | — | |
| SCHEMBL23351061 | 0.83 | — | — | |
| SCHEMBL19346490 | 0.82 | POLB (0.31) | GAA | |
| SCHEMBL23351001 | 0.81 | — | — | |
| SCHEMBL22193802 | 0.78 | NLRP3 (0.36) | GAA | |
| SCHEMBL22745249 | 0.74 | POLB (0.38) | GAA | |
| SCHEMBL19346562 | 0.72 | EGLN1 (0.33) | — | |
| SCHEMBL19329998 | 0.60 | ALDH1A1 (0.32) | GAA | |
| SCHEMBL22745311 | 0.60 | POLB (0.34) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3426656-B1 | TRICYCLIC COMPOUNDS USEFUL TO TREAT ORTHOMYXOVIRUS INFECTIONS | NOVARTIS AG (CH) | 2021-05-12 | — | — | EP | disclosed |
| WO-2017153919-A1 | TRICYCLIC COMPOUNDS USEFUL TO TREAT ORTHOMYXOVIRUS INFECTIONS | NOVARTIS AG (CH) | 2017-09-14 | — | — | WO | disclosed |