Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 6/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL93031 | 0.87 | LMNA (0.42) | LDHAKMT2ATHRATHRBLMNA | |
| SCHEMBL13946439 | 0.85 | KMT2A (0.38) | LDHAKMT2ATHRATHRBLMNA | |
| SCHEMBL4549708 | 0.84 | MAOA (0.39) | LDHAKMT2ALMNAGAAMEN1 | |
| SCHEMBL17934208 | 0.83 | LDHA (0.37) | LDHAKMT2ATHRATHRBLMNA | |
| SCHEMBL10271760 | 0.83 | LMNA (0.40) | LDHAKMT2ALMNAGAACYP1A2 | |
| SCHEMBL28562770 | 0.81 | MEN1 (0.47) | KMT2ATHRATHRBMEN1HPGD | |
| SCHEMBL19346633 | 0.81 | MEN1 (0.36) | LDHAKMT2ALMNAGAAMEN1 | |
| SCHEMBL19346634 | 0.81 | MEN1 (0.36) | LDHAKMT2ALMNAGAAMEN1 | |
| SCHEMBL17831467 | 0.80 | MEN1 (0.38) | LDHAKMT2ALMNAGAAMEN1 | |
| SCHEMBL29142515 | 0.79 | MAOA (0.43) | KMT2ALMNAMEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017153919-A1 | TRICYCLIC COMPOUNDS USEFUL TO TREAT ORTHOMYXOVIRUS INFECTIONS | NOVARTIS AG (CH) | 2017-09-14 | — | — | WO | disclosed |