Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
| ▸ | CLK1 | P49759 | 1/20 | 0.31 |
| ▸ | CLK2 | P49760 | 1/20 | 0.31 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19347967 | 0.85 | ALDH1A1 (0.40) | MTNR1APOLBTSHRMTNR1BSMN1; SMN2 | |
| SCHEMBL22455534 | 0.83 | RAB9A (0.48) | POLBTSHRSMN1; SMN2TP53RAB9A | |
| SCHEMBL5618142 | 0.72 | TSHR (0.40) | POLBTSHRSMN1; SMN2TP53RAB9A | |
| SCHEMBL18646660 | 0.69 | POLB (0.38) | KMT2APOLBTSHR | |
| SCHEMBL1509684 | 0.68 | — | — | |
| SCHEMBL23277327 | 0.66 | — | — | |
| SCHEMBL4545266 | 0.66 | KEAP1 (0.48) | KMT2AMTNR1ATSHRMTNR1BSMN1; SMN2 | |
| SCHEMBL13870744 | 0.66 | SMN1; SMN2 (0.39) | KMT2AMTNR1APOLBMTNR1BSMN1; SMN2 | |
| SCHEMBL12662755 | 0.66 | PIK3CD (0.41) | TSHRSMN1; SMN2TP53RAB9AKDM4E | |
| SCHEMBL23743989 | 0.66 | HPGD (0.61) | SMN1; SMN2RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017153527-A1 | NOVEL INHIBITORS OF PHOSPHATIDYLINOSITOL 3-KINASE GAMMA | ASTRAZENECA AB (SE) | 2017-09-14 | — | — | WO | disclosed |