Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.40 |
| ▸ | AKR1C4 | P17516 | 2/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.40 |
| ▸ | LIMK1 | P53667 | 3/20 | 0.39 |
| ▸ | PLAU | P00749 | 2/20 | 0.37 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | EIF4E | P06730 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.35 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12439761 | 1.00 | GAA (0.43) | GAAAKR1C3AKR1C2AKR1C4AKR1C1 | |
| SCHEMBL12439827 | 0.91 | GAA (0.40) | GAAPLAUNTRK1PIM1NPC1 | |
| SCHEMBL1935230 | 0.91 | GAA (0.40) | GAAPLAUNTRK1PIM1NPC1 | |
| SCHEMBL1935000 | 0.84 | TRPA1 (0.43) | GAAAKR1C3AKR1C2NPC1RAB9A | |
| SCHEMBL12439786 | 0.84 | TRPA1 (0.43) | GAAAKR1C3AKR1C2NPC1RAB9A | |
| SCHEMBL1934577 | 0.83 | ALOX5AP (0.44) | AKR1C3AKR1C2SCN9ADYRK1A | |
| SCHEMBL12439755 | 0.83 | ALOX5AP (0.44) | AKR1C3AKR1C2SCN9ADYRK1A | |
| SCHEMBL12439765 | 0.81 | SCN9A (0.44) | GAAAKR1C3AKR1C2NTRK1PIM1 | |
| SCHEMBL1935601 | 0.81 | SCN9A (0.44) | GAAAKR1C3AKR1C2NTRK1PIM1 | |
| SCHEMBL1934839 | 0.80 | SCN9A (0.48) | GAANPC1RAB9ASCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2332936-B1 | PYRIDINE COMPOUND AND USE THEREOF FOR PEST CONTROL | SUMITOMO CHEMICAL CO (JP) | 2013-09-04 | — | — | EP | disclosed |
| US-20110178132-A1 | PYRIDINE COMPOUND AND USE THEREOF FOR PEST CONTROL | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2011-07-21 | — | — | US | disclosed |
| EP-2332936-A1 | PYRIDINE COMPOUND AND USE THEREOF FOR PEST CONTROL | Sumitomo Chemical Company, Limited (JP) | 2011-06-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110178132-A1 | PYRIDINE COMPOUND AND USE THEREOF FOR PEST CONTROL | C5, PRDX1, PRDX4 | GAA 4246/4885AKR1C3 475/4885AKR1C2 1383/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.