Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 4/20 | 0.60 |
| ▸ | MMP2 | P08253 | 4/20 | 0.60 |
| ▸ | MMP9 | P14780 | 4/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | RECQL | P46063 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.54 |
| ▸ | ARG1 | P05089 | 1/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1934858 | 0.76 | MAOB (0.59) | RECQLMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL6233942 | 0.76 | MMP1 (1.00) | MMP1MMP2MMP9POLBRECQL | |
| SCHEMBL16473431 | 0.76 | MMP1 (1.00) | MMP1MMP2MMP9POLBRECQL | |
| SCHEMBL28891887 | 0.76 | MMP1 (1.00) | MMP1MMP2MMP9POLBRECQL | |
| SCHEMBL1934987 | 0.75 | USP9X (0.72) | POLBRECQLMEN1KMT2AALDH1A1 | |
| SCHEMBL1934696 | 0.74 | SMN1; SMN2 (0.41) | ALDH1A1TAAR1HPGDSMN1; SMN2 | |
| SCHEMBL4661887 | 0.74 | SMN1; SMN2 (0.41) | ALDH1A1TAAR1HPGDSMN1; SMN2 | |
| SCHEMBL30400234 | 0.74 | MMP1 (0.60) | MMP1MMP2MMP9POLBRECQL | |
| SCHEMBL31210243 | 0.74 | MMP1 (0.60) | MMP1MMP2MMP9POLBRECQL | |
| SCHEMBL3614973 | 0.74 | KDM4E (0.53) | ALDH1A1HPGDRAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2506852-A2 | INTERFERON THERAPIES IN COMBINATION WITH BLOCKADE OF STAT3 ACTIVATION | Board Of Regents, The University Of Texas System (US) | 2012-10-10 | — | — | EP | disclosed |
| WO-2011069141-A2 | INTERFERON THERAPIES IN COMBINATION WITH BLOCKADE OF STAT3 ACTIVATION | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2011-06-09 | — | — | WO | disclosed |