Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1934696 | 1.00 | SMN1; SMN2 (0.41) | SMN1; SMN2ALDH1A1HPGDPRMT1GAA | |
| SCHEMBL3707091 | 0.76 | GAA (0.61) | PRMT1GAATAAR1HSD17B10 | |
| SCHEMBL3707088 | 0.76 | GAA (0.61) | PRMT1GAATAAR1HSD17B10 | |
| SCHEMBL1934969 | 0.74 | MMP1 (0.60) | SMN1; SMN2ALDH1A1HPGDTAAR1 | |
| SCHEMBL1315051 | 0.72 | STAT3 (0.48) | ALDH1A1GAA | |
| SCHEMBL1315044 | 0.72 | STAT3 (0.48) | ALDH1A1GAA | |
| SCHEMBL1315046 | 0.72 | STAT3 (0.48) | ALDH1A1GAA | |
| SCHEMBL13474828 | 0.72 | STAT3 (0.48) | ALDH1A1GAA | |
| SCHEMBL1315048 | 0.72 | STAT3 (0.48) | ALDH1A1GAA | |
| SCHEMBL14495263 | 0.71 | NFE2L2 (0.39) | ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2007714-A2 | ORALLY BIOAVAILABLE CAFFEIC ACID RELATED ANTICANCER DRUGS | The Board of Regents of The University of Texas System (US) | 2008-12-31 | — | — | EP | disclosed |
| WO-2007115269-A2 | ORALLY BIOAVAILABLE CAFFEIC ACID RELATED ANTICANCER DRUGS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2007-10-11 | — | — | WO | disclosed |