Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | PGR | P06401 | 1/20 | 0.49 |
| ▸ | FABP7 | O15540 | 1/20 | 0.48 |
| ▸ | FABP3 | P05413 | 1/20 | 0.48 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | BLM | P54132 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | ESRRA | P11474 | 1/20 | 0.41 |
| ▸ | TOP1 | P11387 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9476254 | 0.80 | KDM4E (0.50) | ALDH1A1GAAMAPK1PTGS1HSD17B10 | |
| SCHEMBL26036680 | 0.80 | MAOB (0.50) | ALDH1A1GAAMAPK1PTGS1HSD17B10 | |
| SCHEMBL18540824 | 0.79 | NQO1 (0.46) | ALDH1A1GAAMAPK1PTGS1HSD17B10 | |
| SCHEMBL7820963 | 0.78 | CASP6 (0.58) | ALDH1A1GAAMAPK1PTGS1HSD17B10 | |
| SCHEMBL13675023 | 0.78 | KMT2A (0.46) | ALDH1A1GAAMAPK1PTGS1HSD17B10 | |
| SCHEMBL4328550 | 0.77 | ALDH1A1 (0.58) | ALDH1A1GAAMAPK1PTGS1HSD17B10 | |
| SCHEMBL7099992 | 0.77 | MTNR1A (0.52) | ALDH1A1GAAHSD17B10KDM4EKMT2A | |
| SCHEMBL27626362 | 0.77 | ALDH1A1 (0.36) | ALDH1A1GAAMAPK1PTGS1HSD17B10 | |
| Alpha-Naphthylacetate SCHEMBL76633 | 0.77 | ALDH1A1 (0.66) | ALDH1A1GAAMAPK1PTGS1HSD17B10 | |
| Alpha-Naphthylacetate SCHEMBL29372782 | 0.77 | ALDH1A1 (0.66) | ALDH1A1GAAMAPK1PTGS1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017156354-A1 | α-TRUXILLIC ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS THEREOF | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2017-09-14 | — | — | WO | disclosed |