Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | GALR3 | O60755 | 1/20 | 0.44 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.44 |
| ▸ | GPR183 | P32249 | 1/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 6/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1627210 | 0.78 | SMN1; SMN2 (0.50) | SMN1; SMN2KMT2ANPC1MEN1LMNA | |
| SCHEMBL17738012 | 0.77 | SMN1; SMN2 (0.50) | SMN1; SMN2KMT2ANPC1MEN1LMNA | |
| SCHEMBL11272569 | 0.75 | SMN1; SMN2 (0.46) | SMN1; SMN2KMT2ANPC1MEN1LMNA | |
| SCHEMBL27619400 | 0.75 | SMN1; SMN2 (0.46) | SMN1; SMN2KMT2ANPC1MEN1LMNA | |
| SCHEMBL3847199 | 0.75 | SMN1; SMN2 (0.46) | SMN1; SMN2KMT2ANPC1MEN1LMNA | |
| SCHEMBL1627207 | 0.75 | SMN1; SMN2 (0.46) | SMN1; SMN2KMT2ANPC1MEN1LMNA | |
| SCHEMBL5275461 | 0.73 | HPGD (0.31) | SMN1; SMN2HPGD | |
| SCHEMBL21511152 | 0.72 | SMN1; SMN2 (0.57) | SMN1; SMN2KMT2ANPC1MEN1LMNA | |
| SCHEMBL7016487 | 0.72 | SMN1; SMN2 (0.51) | SMN1; SMN2KMT2ANPC1MEN1LMNA | |
| SCHEMBL8543541 | 0.71 | SMN1; SMN2 (0.64) | SMN1; SMN2KMT2ANPC1MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170258947-A1 | METHODS AND APPARATUS FOR SYNTHESIZING IMAGING AGENTS, AND INTERMEDIATES THEREOF | LANTHEUS MEDICAL IMAGING, INC. (US) | 2017-09-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170258947-A1 | METHODS AND APPARATUS FOR SYNTHESIZING IMAGING AGENTS, AND INTERMEDIATES THEREOF | TNNI3, FABP3, MPI | SMN1; SMN2 2628/4885KMT2A 4371/4885NPC1 1259/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.