Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | GALR3 | O60755 | 1/20 | 0.46 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.46 |
| ▸ | GPR183 | P32249 | 1/20 | 0.46 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 5/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11272569 | 0.81 | SMN1; SMN2 (0.46) | SMN1; SMN2NPC1KMT2ALMNARAB9A | |
| SCHEMBL1627210 | 0.81 | SMN1; SMN2 (0.50) | SMN1; SMN2NPC1KMT2ALMNARAB9A | |
| SCHEMBL9233800 | 0.81 | TSHR (0.39) | SMN1; SMN2NPC1KMT2ALMNARAB9A | |
| SCHEMBL17738012 | 0.79 | SMN1; SMN2 (0.50) | SMN1; SMN2NPC1KMT2ALMNARAB9A | |
| SCHEMBL3847199 | 0.78 | SMN1; SMN2 (0.46) | SMN1; SMN2NPC1KMT2ALMNARAB9A | |
| SCHEMBL1627207 | 0.78 | SMN1; SMN2 (0.46) | SMN1; SMN2NPC1KMT2ALMNARAB9A | |
| SCHEMBL21718646 | 0.76 | TSHR (0.35) | SMN1; SMN2NPC1KMT2ALMNARAB9A | |
| SCHEMBL19356550 | 0.75 | SMN1; SMN2 (0.44) | SMN1; SMN2NPC1KMT2ALMNARAB9A | |
| SCHEMBL21511152 | 0.75 | SMN1; SMN2 (0.57) | SMN1; SMN2NPC1KMT2ALMNARAB9A | |
| SCHEMBL7016487 | 0.75 | SMN1; SMN2 (0.51) | SMN1; SMN2NPC1KMT2ALMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1651416-A | Preparation method of 5-fluoro-3(2H)-pyridazinone compound | UNIV ZHEJIANG POLYTECHNIC (CN) | 2005-08-10 | — | — | CN | disclosed |