Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.65 |
| ▸ | NPC1 | O15118 | 5/20 | 0.64 |
| ▸ | RAB9A | P51151 | 6/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | ELOVL1 | Q9BW60 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.57 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.57 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.57 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2753301 | 0.82 | LMNA (0.71) | LMNANPC1RAB9AKMT2AELOVL1 | |
| SCHEMBL17107238 | 0.81 | RAB9A (0.70) | LMNANPC1RAB9AKMT2AELOVL1 | |
| SCHEMBL19357131 | 0.79 | LMNA (1.00) | LMNANPC1RAB9AKMT2AELOVL1 | |
| SCHEMBL3455457 | 0.79 | MAPT (0.60) | LMNANPC1RAB9AKMT2AELOVL1 | |
| SCHEMBL225327 | 0.79 | ELOVL1 (0.74) | LMNANPC1RAB9AKMT2AELOVL1 | |
| SCHEMBL8402291 | 0.78 | MAPT (0.73) | LMNANPC1RAB9AKMT2AELOVL1 | |
| SCHEMBL2452315 | 0.78 | ELOVL1 (0.72) | LMNANPC1RAB9AKMT2AELOVL1 | |
| SCHEMBL21224224 | 0.78 | ELOVL1 (0.72) | LMNANPC1RAB9AKMT2AELOVL1 | |
| SCHEMBL1357607 | 0.78 | ELOVL1 (0.72) | LMNANPC1RAB9AKMT2AELOVL1 | |
| SCHEMBL27982784 | 0.77 | LMNA (0.45) | LMNANPC1RAB9AKMT2AELOVL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017157882-A1 | SERINE BIOSYNTHETIC PATHWAY INHIBITORS | Université Catholique de Louvain (BE) | 2017-09-21 | — | — | WO | claimed |
| WO-2017157882-A1 | SERINE BIOSYNTHETIC PATHWAY INHIBITORS | Université Catholique de Louvain (BE) | 2017-09-21 | — | — | WO | disclosed |