Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKD3 | O94806 | 3/20 | 0.34 |
| ▸ | PRKCG | P05129 | 3/20 | 0.34 |
| ▸ | PRKCB | P05771 | 3/20 | 0.34 |
| ▸ | PRKCA | P17252 | 3/20 | 0.34 |
| ▸ | PRKCH | P24723 | 3/20 | 0.34 |
| ▸ | PRKCI | P41743 | 3/20 | 0.34 |
| ▸ | PRKCE | Q02156 | 3/20 | 0.34 |
| ▸ | PRKCQ | Q04759 | 3/20 | 0.34 |
| ▸ | PRKCZ | Q05513 | 3/20 | 0.34 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.34 |
| ▸ | PRKD1 | Q15139 | 3/20 | 0.34 |
| ▸ | PRKACA | P17612 | 1/20 | 0.34 |
| ▸ | PRKACG | P22612 | 1/20 | 0.34 |
| ▸ | PRKACB | P22694 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2380693 | 0.76 | NT5E (0.40) | MEN1KMT2APKMSMN1; SMN2ALDH1A1 | |
| SCHEMBL301992 | 0.76 | MEN1 (0.30) | MEN1KMT2APKMSMN1; SMN2ALDH1A1 | |
| SCHEMBL2405485 | 0.71 | MEN1 (0.49) | MEN1KMT2APKMSMN1; SMN2ALDH1A1 | |
| Potassium Ion SCHEMBL9152245 | 0.67 | — | — | |
| SCHEMBL170998 | 0.62 | ALDH1A1 (0.39) | MEN1KMT2APKMSMN1; SMN2ALDH1A1 | |
| SCHEMBL15528926 | 0.61 | MEN1 (0.68) | MEN1KMT2APKMSMN1; SMN2ALDH1A1 | |
| SCHEMBL27426620 | 0.61 | CASP6 (0.38) | MEN1KMT2APKMSMN1; SMN2ALDH1A1 | |
| SCHEMBL28120681 | 0.60 | MEN1 (0.39) | MEN1KMT2APKMSMN1; SMN2ALDH1A1 | |
| SCHEMBL17145936 | 0.60 | GSK3B (0.45) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL3982795 | 0.59 | ALDH1A1 (0.49) | PRKD3PRKCGPRKCBPRKCAPRKCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3430015-A1 | METHODS TO DETERMINE KDM1A TARGET ENGAGEMENT AND CHEMOPROBES USEFUL THEREFOR | Oryzon Genomics, S.A. (ES) | 2019-01-23 | — | — | EP | disclosed |
| WO-2017158136-A1 | METHODS TO DETERMINE KDM1A TARGET ENGAGEMENT AND CHEMOPROBES USEFUL THEREFOR | ORYZON GENOMICS, S.A. (ES) | 2017-09-21 | — | — | WO | disclosed |