SCHEMBL301992

SCHEMBL301992

NCCNc1c(S(=O)(=O)O)cc2c3c(cc(S(=O)(=O)O)cc13)C(=O)NC2=O

nearest known ligand 0.40

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 1/20 0.30
▸ PKM P14618 1/20 0.30
▸ KMT2A Q03164 1/20 0.30
▸ SMN1; SMN2 Q16637 1/20 0.30
▸ ALDH1A1 P00352 1/20 0.30
▸ CYP2C9 P11712 1/20 0.30
▸ CYP2C19 P33261 1/20 0.30
▸ CASP6 P55212 1/20 0.30
▸ HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL263329 0.92 PRKD3 (0.33) MEN1KMT2AALDH1A1CYP2C9CYP2C19
Potassium Ion SCHEMBL9152245 0.84 — —
SCHEMBL170998 0.77 ALDH1A1 (0.39) MEN1PKMKMT2ASMN1; SMN2ALDH1A1
SCHEMBL19357602 0.76 PRKD3 (0.34) MEN1PKMKMT2ASMN1; SMN2ALDH1A1
SCHEMBL27426620 0.76 CASP6 (0.38) MEN1PKMKMT2ASMN1; SMN2ALDH1A1
SCHEMBL28120681 0.72 MEN1 (0.39) MEN1PKMKMT2ASMN1; SMN2ALDH1A1
SCHEMBL9293198 0.69 CASP6 (0.47) MEN1KMT2ASMN1; SMN2ALDH1A1CYP2C9
SCHEMBL2405485 0.67 MEN1 (0.49) MEN1PKMKMT2ASMN1; SMN2ALDH1A1
SCHEMBL4432678 0.64 — —
SCHEMBL21404284 0.63 CLTC (0.40) MEN1KMT2AALDH1A1CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0853680-B1 METHOD FOR PRECIPITATING NUCLEIC ACID WITH VISIBLE CARRIER EMD BIOSCIENCES INC (US) 2004-03-31 — — EP claimed
WO-2024148174-A1 PEPTIDE SEQUENCER OREGON HEALTH & SCIENCE UNIVERSITY (US) 2024-07-11 — — WO disclosed
EP-3500595-B1 ANTI-PSMA ANTIBODIES, USES THEREOF AND CONJUGATES THEREOF ABZENA UK LTD (GB) 2024-05-01 — — EP disclosed
US-11865183-B2 Conjugates and conjugating reagents comprising a linker that includes at least two (−CH2—CH2—O—) units in a ring POLYTHERICS LIMITED (GB) 2024-01-09 — — US disclosed
EP-4282434-A2 ANTIBODIES, USES THEREOF AND CONJUGATES THEREOF Abzena (UK) Limited (GB) 2023-11-29 — — EP disclosed
EP-3464379-B1 ANTIBODIES, USES THEREOF AND CONJUGATES THEREOF ABZENA UK LTD (GB) 2023-09-27 — — EP disclosed
EP-3220956-B1 CONJUGATES AND CONJUGATING REAGENTS ABZENA UK LTD (GB) 2023-08-09 — — EP disclosed
US-11485792-B2 Antibodies, uses thereof and conjugates thereof POLYTHERICS LIMITED 2022-11-01 — — US disclosed
CN-109152845-B Comprising at least two (-CH) s within a ring2-CH2Conjugates of linkers of-O-) units and conjugation reagents 宝力泰锐克斯有限公司 2022-07-12 — — CN disclosed
CN-109152846-B Conjugates and conjugation reagents 宝力泰锐克斯有限公司 2022-07-08 — — CN disclosed
US-20070178601-A1 METHOD FOR PRECIPITATING NUCLEIC ACID WITH VISIBLE CARRIER EMD BIOSCIENCES, INC. 2007-08-02 — — US disclosed
US-20070173470-A1 Methods for delivering extracellular target into cells NATIONAL YANG-MING UNIVERSITY (TW) 2007-07-26 — — US disclosed
US-7144713-B1 Method for precipitating nucleic acid with visible carrier EMD BIOSCIENCES, INC. (US) 2006-12-05 — — US disclosed
EP-0853680-B1 METHOD FOR PRECIPITATING NUCLEIC ACID WITH VISIBLE CARRIER EMD BIOSCIENCES INC (US) 2004-03-31 — — EP disclosed
EP-1129345-A1 PRACTICAL DEVICE FOR CONTROLLING ULTRASMALL VOLUME FLOW ARIZONA BOARD OF REGENTS (US) 2001-09-05 — — EP disclosed
WO-2000028315-A1 PRACTICAL DEVICE FOR CONTROLLING ULTRASMALL VOLUME FLOW ARIZONA BOARD OF REGENTS (US) 2000-05-18 — — WO disclosed
EP-0515379-A4 ELECTRO-BLOTTING OF ELECTROPHORETICALLY RESOLVED FLUORESCENT-LABELED SACCHARIDES AND DETECTION OF ACTIVE STRUCTURES WITH PROTEIN PROBES GLYCOMED INC (US) 1994-09-14 — — EP disclosed
EP-0515379-A1 ELECTRO-BLOTTING OF ELECTROPHORETICALLY RESOLVED FLUORESCENT-LABELED SACCHARIDES AND DETECTION OF ACTIVE STRUCTURES WITH PROTEIN PROBES GLYCOMED INCORPORATED (US) 1992-12-02 — — EP disclosed
US-5094731-A ELECTRO-BLOTTING OF ELECTROPHORETICALLY RESOLVED FLUORESCENT-LABELED SACCHARIDES AND DETECTION OF ACTIVE STRUCTURES WITH PROTEIN PROBES GLYCOMED, INC. (US) 1992-03-10 — — US disclosed
WO-1991012276-A1 ELECTRO-BLOTTING OF ELECTROPHORETICALLY RESOLVED FLUORESCENT-LABELED SACCHARIDES AND DETECTION OF ACTIVE STRUCTURES WITH PROTEIN PROBES GLYCOMED INCORPORATED (US) 1991-08-22 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11485792-B2 Antibodies, uses thereof and conjugates thereof KLK3, VSIG8, IGLV6-57 MEN1 818/4885PKM 2121/4885KMT2A 96/4885
US-11865183-B2 Conjugates and conjugating reagents comprising a linker that includes at least two (−CH2—CH2—O—) units in a ring BCR, CD2BP2, LANCL2 MEN1 331/4885PKM 4261/4885KMT2A 798/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback