SCHEMBL170998

SCHEMBL170998

Nc1c(S(=O)(=O)O)cc2c3c(cc(S(=O)(=O)O)cc13)C(=O)NC2=O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 6/20 0.39
▸ CYP2C9 P11712 3/20 0.39
▸ CASP6 P55212 3/20 0.39
▸ HSD17B10 Q99714 3/20 0.39
▸ CYP2C19 P33261 2/20 0.39
▸ MEN1 O00255 4/20 0.35
▸ KMT2A Q03164 4/20 0.35
▸ PKM P14618 2/20 0.35
▸ SMN1; SMN2 Q16637 1/20 0.35
▸ NT5E P21589 3/20 0.34
▸ TDP1 Q9NUW8 4/20 0.33
▸ MAPT P10636 3/20 0.33
▸ THRB P10828 3/20 0.33
▸ BLM P54132 3/20 0.33
▸ APEX1 P27695 2/20 0.33
▸ RECQL P46063 2/20 0.33
▸ CYP1A2 P05177 2/20 0.33
▸ CYP3A4 P08684 2/20 0.33
▸ RGS12 O14924 1/20 0.33
▸ USP2 O75604 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27426620 0.99 CASP6 (0.38) ALDH1A1CYP2C9CASP6HSD17B10CYP2C19
SCHEMBL1615000 0.82 ALDH1A1 (0.39) ALDH1A1CYP2C9CASP6HSD17B10CYP2C19
SCHEMBL28120681 0.81 MEN1 (0.39) ALDH1A1CYP2C9CASP6HSD17B10CYP2C19
SCHEMBL2380693 0.79 NT5E (0.40) ALDH1A1CYP2C9CASP6HSD17B10CYP2C19
SCHEMBL2405485 0.77 MEN1 (0.49) ALDH1A1CYP2C9CASP6HSD17B10CYP2C19
SCHEMBL21946061 0.77 CLTC (0.36) ALDH1A1CYP2C9CASP6HSD17B10CYP2C19
SCHEMBL301992 0.77 MEN1 (0.30) ALDH1A1CYP2C9CASP6HSD17B10CYP2C19
SCHEMBL21404284 0.76 CLTC (0.40) ALDH1A1CYP2C9CASP6HSD17B10CYP2C19
Ethylenediamine SCHEMBL21957845 0.75 CLTC (0.39) ALDH1A1CYP2C9CASP6HSD17B10CYP2C19
SCHEMBL27404612 0.75 CLTC (0.39) ALDH1A1CYP2C9CASP6HSD17B10CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 470 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2167536-A1 MHC MULTIMERS, METHODS FOR THEIR GENERATION, LABELING AND USE Dako Denmark A/S (DK) 2010-03-31 — — EP claimed
WO-2009003492-A1 MHC MULTIMERS, METHODS FOR THEIR GENERATION, LABELING AND USE DAKO DENMARK A/S (DK) 2009-01-08 — — WO claimed
WO-2024152018-A2 SYSTEMS AND METHODS FOR LIBRARY PREPARATION ADAPTERS ULTIMA GENOMICS, INC. (US) 2024-07-18 — — WO disclosed
US-12031180-B2 Methods, devices, and systems for analyte detection and analysis ULTIMA GENOMICS, INC. (US) 2024-07-09 — — US disclosed
US-20240212150-A1 MATERIALS AND METHODS RELATED TO IMAGE PROCESSING ADVANCED CELL DIAGNOSTICS, INC. 2024-06-27 — — US disclosed
US-20240209423-A1 METHODS AND COMPOSITIONS FOR REDUCING AUTOFLUORESCENCE ADVANCED CELL DIAGNOSTICS, INC. 2024-06-27 — — US disclosed
WO-2024137873-A1 QUANTIFICATION OF CO-LOCALIZED TAG SEQUENCES USING ORTHOGONAL SEQUENCE ENCODING ULTIMA GENOMICS, INC. (US) 2024-06-27 — — WO disclosed
EP-4388129-A2 SYSTEMS AND METHODS FOR SAMPLE PREPARATION FOR SEQUENCING Ultima Genomics, Inc. (US) 2024-06-26 — — EP disclosed
EP-4384279-A1 METHODS FOR TREATING NON-MUSCLE INVASIVE BLADDER CANCER (NMIBC) WITH ANTIBODY DRUG CONJUGATES (ADC) THAT BIND TO 191P4D12 PROTEINS Agensys, Inc. (US) 2024-06-19 — — EP disclosed
CN-118203673-A Methods of treating cancer with Antibody Drug Conjugates (ADCs) that bind to 191P4D12 protein 艾更斯司股份有限公司 2024-06-18 — — CN disclosed
WO-2024124041-A1 MULTIPLEXED DETECTION OF NUCLEIC ACID TARGETS ADVANCED CELL DIAGNOSTICS, INC. (US) 2024-06-13 — — WO disclosed
US-20040038319-A1 Chemical reagents and methods for detection and quantification of proteins in complex mixtures INSTITUTE FOR SYSTEMS BIOLOGY, THE 2004-02-26 — — US disclosed
EP-1352091-A2 COMPOSITIONS AND METHODS ENABLING A TOTALLY INTERNALLY CONTROLLED AMPLIFICATION REACTION Cepheid (US) 2003-10-15 — — EP disclosed
US-20030064368-A1 Methods, apparatus, and computer programs for verifying the integrity of a probe CEPHEID 2003-04-03 — — US disclosed
US-6534645-B2 Amplifying preferential nucleotide sequences; obtain nucleotide sequences, incubate primers and probes, amplify, measure binding of the target probe CEPHEID 2003-03-18 — — US disclosed
WO-2003009100-A2 METHODS, APPARATUSES, AND COMPUTER PROGRAMS FOR VERIFYING THE INTEGRITY OF A PROBE CEPHEID (US) 2003-01-30 — — WO disclosed
US-20020119464-A1 Compositions and methods enabling a totally internally controlled amplification reaction MCMILLAN WILLIAM A (US) 2002-08-29 — — US disclosed
WO-2002052030-A2 COMPOSITIONS AND METHODS ENABLING A TOTALLY INTERNALLY CONTROLLED AMPLIFICATION REACTION CEPHEID (US) 2002-07-04 — — WO disclosed
US-6312929-B1 AMPLIFYING PREFERENTIAL NUCLEOTIDE SEQUENCES; MIX PROBES, PRIMER AND NUCLEOTIDE SEQUENCES IN SOLUTION, AMPLIFY NUCLEOTIDE SEQUENCES, MONITOR BINDING OF PROBE CEPHEID 2001-11-06 — — US disclosed
CN-1104331-A Method for detection of sulfides NALCO CHEMICAL CO (US) 1995-06-28 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040038319-A1 Chemical reagents and methods for detection and quantification of proteins in complex mixtures STUB1, INHA, IAPP ALDH1A1 3856/4885CYP2C9 4645/4885CASP6 4749/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback